Efficacy/Safety of ALTB-268 in Subjects w/Moderately to Severely Active UC Refractory to Biologics
- First Posted Date
- 2023-10-31
- Last Posted Date
- 2025-02-18
- Lead Sponsor
- AltruBio Inc.
- Target Recruit Count
- 30
- Registration Number
- NCT06109441
- Locations
- ๐บ๐ธ
San Diego Gastroenterology, San Diego, California, United States
๐บ๐ธRocky Mountain Gastroenterology, Littleton, Colorado, United States
๐บ๐ธGastro Health Research, Miami, Florida, United States
A First-In-Human SAD and MAD Study to Evaluate the Safety, Tolerability, PK and PD of SC Administered ALTB-268 in Healthy Volunteers
Phase 1
Completed
- Conditions
- Healthy Volunteers
- Interventions
- Other: PlaceboBiological: ALTB-268
- First Posted Date
- 2023-02-13
- Last Posted Date
- 2024-02-06
- Lead Sponsor
- AltruBio Inc.
- Target Recruit Count
- 56
- Registration Number
- NCT05723692
- Locations
- ๐บ๐ธ
ICON Early Development Services, Lenexa, Kansas, United States
Neihulizumab (ALTB-168) in Patients With Steroid-refractory Acute Graft-versus-host Disease or Treatment-refractory Acute Graft-versus-host Disease
Phase 1
Completed
- Conditions
- Treatment-refractory Acute Graft-versus-Host DiseaseSteroid-refractory Acute Graft-versus-Host Disease
- Interventions
- Biological: Neihulizumab (ALTB-168)
- First Posted Date
- 2017-11-01
- Last Posted Date
- 2023-01-19
- Lead Sponsor
- AltruBio Inc.
- Target Recruit Count
- 37
- Registration Number
- NCT03327857
- Locations
- ๐บ๐ธ
David Geffen School of Medicine at UCLA, Los Angeles, California, United States
๐บ๐ธBaylor College of Medicine-Houston Methodist & Texas Children's Hospital, Houston, Texas, United States
๐บ๐ธUniversity of Miami - Sylvester Comprehensive Cancer Center, Miami, Florida, United States
Efficacy&Safety of ALTB-168 in Patients With Moderate to Severe Active,Anti-TNF Alpha and/or Anti-integrin Refractory UC
Phase 2
Terminated
- Conditions
- Ulcerative Colitis
- Interventions
- Biological: ALTB-168
- First Posted Date
- 2017-09-29
- Last Posted Date
- 2024-01-05
- Lead Sponsor
- AltruBio Inc.
- Target Recruit Count
- 24
- Registration Number
- NCT03298022
- Locations
- ๐ต๐ท
Wellness Clinical Research (WCR), Vega Baja, Puerto Rico
๐บ๐ธLynn Institute of the Ozarks, Little Rock, Arkansas, United States
๐บ๐ธUniversity of Rochester Medical Center, Rochester, New York, United States
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