Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries
- Conditions
- Metatarsophalangeal FushionLower Extremity SurgeryMidfoot FusionTotal Ankle ArthroplastyBunionHindfoot Fushion
- Interventions
- First Posted Date
- 2020-08-19
- Last Posted Date
- 2022-07-18
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 121
- Registration Number
- NCT04518462
- Locations
- 🇺🇸
Lotus Clinical Research, Pasadena, California, United States
🇺🇸HD Research, Corp, Bellaire, Texas, United States
🇺🇸Arizona Research Center, Phoenix, Arizona, United States
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a Pectoral Plane Block in Women Undergoing Breast Augmentation
- Conditions
- Breast Augmentation
- Interventions
- First Posted Date
- 2020-03-03
- Last Posted Date
- 2024-01-29
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 30
- Registration Number
- NCT04293809
- Locations
- 🇺🇸
HD Research, Bellaire, Texas, United States
Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty
- Conditions
- Post-Operative Pain Management
- Interventions
- Device: ioveraº shamDevice: ioveraº
- First Posted Date
- 2019-12-09
- Last Posted Date
- 2023-01-25
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 79
- Registration Number
- NCT04191031
- Locations
- 🇺🇸
Phoenix Clinical Research, Tamarac, Florida, United States
🇺🇸Sah Orthopaedic Associates at the Institute for Joint Restoration, Fremont, California, United States
🇺🇸Legent Orthopedic Hospital, Carrollton, Texas, United States
Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Administered Via a Single Intrathecal Injection to Healthy Volunteers
- Conditions
- Healthy
- Interventions
- First Posted Date
- 2019-11-22
- Last Posted Date
- 2021-05-06
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 20
- Registration Number
- NCT04173611
- Locations
- 🇺🇸
Duke University, Durham, North Carolina, United States
Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis
- Conditions
- Osteoarthritis of the ShoulderAdhesive Capsulitis
- Interventions
- Drug: Normal Saline
- First Posted Date
- 2019-11-12
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 19
- Registration Number
- NCT04160091
- Locations
- 🇺🇸
Coastal Clinical Research, Inc., Mobile, Alabama, United States
🇺🇸Gulfcoast Research Institute, Sarasota, Florida, United States
🇺🇸Coastal Orthopaedics and Sports Medicine, Bradenton, Florida, United States
Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoarthritis of the Knee
- First Posted Date
- 2019-10-08
- Last Posted Date
- 2025-03-17
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 72
- Registration Number
- NCT04119687
- Locations
- 🇺🇸
Arizona Research Center, Phoenix, Arizona, United States
🇺🇸Gulfcoast Research Institute, LLC, Sarasota, Florida, United States
🇺🇸Center for Pharmaceutical Research, Kansas City, Missouri, United States
Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patients With Osteoarthritis of the Hip
- Conditions
- Osteoarthritis, Hip
- Interventions
- Drug: FX006 32 mg
- First Posted Date
- 2019-08-22
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 16
- Registration Number
- NCT04065074
- Locations
- 🇺🇸
Lenox Hill Hospital, New York, New York, United States
🇺🇸Hope Clinical Research, Canoga Park, California, United States
🇺🇸Biosolutions Clinical Research Center, La Mesa, California, United States
Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Block (In Popliteal Fossa), for Postsurgical Analgesia in Subjects Undergoing Bunionectomy
- First Posted Date
- 2019-06-28
- Last Posted Date
- 2021-01-11
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 45
- Registration Number
- NCT04002089
- Locations
- 🇺🇸
First Surgical Hospital, Bellaire, Texas, United States
EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture
- Conditions
- Hip FracturesIntertrochanteric Fractures
- Interventions
- First Posted Date
- 2019-05-20
- Last Posted Date
- 2020-02-27
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Registration Number
- NCT03955458
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity Surgeries
- Conditions
- BunionMetatarsophalangeal FusionMidfoot FusionHindfoot FusionTotal Ankle ArthroplastyForefoot Surgery
- Interventions
- First Posted Date
- 2019-05-17
- Last Posted Date
- 2020-08-13
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Registration Number
- NCT03954639