Clinical Trials
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Trial Phases
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Clinical Trials
Distribution across different clinical trial phases (1891 trials with phase data)• Click on a phase to view related trials
Small Trial of Alendronate Impact on the Reservoir of HIV
- First Posted Date
- 2025-10-15
- Last Posted Date
- 2025-10-15
- Target Recruit Count
- 30
- Registration Number
- NCT07216794
- Locations
- 🇺🇸
University of California, San Francisco HIV/AIDS (Site ID: 801), San Francisco, California, United States
🇺🇸University of Colorado Hospital (Site ID: 6101), Aurora, Colorado, United States
🇺🇸Chapel Hill (Site ID: 3201), Chapel Hill, North Carolina, United States
BPL-1357 Against H1N1 Influenza Virus Challenge
- Conditions
- InfluenzaHuman
- Interventions
- Biological: BPL-1357 IMBiological: BPL-1357 INOther: Placebo INOther: Placebo IM
- First Posted Date
- 2025-10-14
- Last Posted Date
- 2025-10-14
- Target Recruit Count
- 126
- Registration Number
- NCT07215858
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
🇺🇸University of Texas Medical Branch, Galveston, Galveston, Texas, United States
Rechallenge With a Low Pathogenicity Avian H10N7 Influenza Virus in Healthy Human Volunteers Previously Challenged With H10N7 Influenza
- Conditions
- Influenza InfectionInfectionsRespiratory Virus InfectionsRespiratory Tract InfectionsRNA VirusesOrthomyxoviridae InfectionsViral Diseases
- Interventions
- Biological: A/Mallard/Ohio-99/MM4/1989 H10N7
- First Posted Date
- 2025-10-14
- Last Posted Date
- 2025-10-16
- Target Recruit Count
- 33
- Registration Number
- NCT07215871
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
L9LS-R21 Interaction
- Conditions
- Malaria
- Interventions
- Drug: Single dose of 1800 mg L9LS SC (12mL)Drug: Single dose of 225 mg L9LS SC (1.5mL)Other: Placebo 12 mL SCOther: Placebo 1.5 mL SC
- First Posted Date
- 2025-10-06
- Last Posted Date
- 2025-10-06
- Target Recruit Count
- 357
- Registration Number
- NCT07208760
- Locations
- 🇲🇱
Sotuba Malaria Research and Training Center (MRTC), Sotouba, Mali
Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis
- Conditions
- Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Enteritis
- Interventions
- First Posted Date
- 2025-10-02
- Last Posted Date
- 2025-10-16
- Target Recruit Count
- 10
- Registration Number
- NCT07202598
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
- Prev
- 1
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News
Single-Dose Benzathine Penicillin G Proves as Effective as Three-Dose Regimen for Early Syphilis Treatment
A randomized clinical trial of 249 participants found that a single injection of benzathine penicillin G achieved 76% serologic response compared to 70% with the three-dose regimen at 6 months.
NIH Awards $8.4 Million to OHSU Scientists to Develop HIV Cure Through Study of Three Cured Patients
Oregon Health & Science University researchers received $8.4 million from the National Institute of Allergy and Infectious Diseases to study three individuals who were cured of HIV through stem cell transplants.
Capricor Therapeutics Initiates First-in-Human Trial of StealthX Exosome-Based Vaccine Platform
Capricor Therapeutics has dosed the first subjects in a Phase 1 clinical trial of its StealthX exosome-based vaccine, marking the first-in-human evaluation of this novel platform.
Soligenix Advances SGX943 as Novel Antibiotic Alternative to Combat Drug-Resistant Bacterial Infections
Soligenix is developing SGX943 (dusquetide), a novel broad-spectrum therapy designed to treat bacterial infections without relying on conventional antibiotics.
Saint Louis University Launches Phase 1 Trial for Investigational West Nile Virus Vaccine
Saint Louis University's Center for Vaccine Development will enroll up to 30 healthy adult volunteers in a Phase 1 clinical trial to evaluate the safety and immune response of an updated investigational West Nile virus vaccine.
HHS and NIH Launch "Generation Gold Standard" Universal Vaccine Platform to Combat Pandemic Threats
The U.S. Department of Health and Human Services and NIH have announced "Generation Gold Standard," a next-generation universal vaccine platform using beta-propiolactone-inactivated whole-virus technology.
Three Pharmaceutical Companies Advance Next-Generation COVID-19 Therapeutics in Clinical Trials
INOVIO Pharmaceuticals reports promising Phase I results for its DMAbs technology, showing 100% of subjects maintained relevant antibody levels with no serious adverse events.
NIH Launches First Clinical Trial of Moderna's mRNA Vaccine Against Deadly Nipah Virus
The National Institutes of Health has initiated the first human trial of Moderna's mRNA-1215 vaccine targeting Nipah virus, a deadly pathogen with a 40-70% fatality rate.
HIV Cure Trials at CROI 2025 Show Promise for Broader Patient Applications
At the 2025 Conference on Retroviruses and Opportunistic Infections (CROI), researchers presented promising results from multiple HIV cure trials, suggesting potential for wider therapeutic applications.
NIH Launches First Human Trial of LASSARAB Vaccine for Deadly Lassa Fever
The NIH has initiated a Phase 1 clinical trial of LASSARAB, a novel vaccine candidate for Lassa fever, a viral hemorrhagic disease that can be fatal and causes permanent hearing loss in up to one-third of patients.