BAYLOR COLLEGE OF MEDICINE

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1900-10-30

Employees: 10K

Market Cap: -

Website: http://www.bcm.edu

Clinical Trials

Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer

Phase 2

Recruiting

Conditions: Pancreatic Ductal Adenocarcinoma

Interventions: Drug: Pembrolizumab
Drug: Folfirinox

First Posted Date: 2021-11-24

Last Posted Date: 2025-01-16

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 30

Registration Number: NCT05132504

Locations: 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
🇺🇸
Baylor St. Luke's Medical Center (BSLMC)., Houston, Texas, United States
🇺🇸
Houston Methodist Hospital, Houston, Texas, United States

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Phase 1

Recruiting

Conditions: Rhabdomyosarcoma
Malignant Rhabdoid Tumor
Liver Cell Carcinoma
Embryonal Sarcoma of the Liver
Solid Tumor
Wilms Tumor
Yolk Sac Tumor
Liposarcoma

Interventions: Genetic: CATCH T cells

First Posted Date: 2021-11-02

Last Posted Date: 2024-11-08

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 27

Registration Number: NCT05103631

Locations: 🇺🇸
Houston Methodist Hospital, Houston, Texas, United States

Effect of Opioids on Central Control of Ventilation in Children With Obstructive Sleep Apnea

Early Phase 1

Completed

Conditions: OSA
Opioid
Adenotonsillectomy

Interventions: Drug: Fentanyl Citrate

First Posted Date: 2021-09-21

Last Posted Date: 2025-04-06

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 90

Registration Number: NCT05051189

Locations: 🇺🇸
Texas childrens Hospital, Houston, Texas, United States

Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL)

Phase 1

Recruiting

Conditions: Leukemia, B-Cell

Interventions: Genetic: Autologous TRICAR-ALL T-cells and lymphodepletion chemotherapy

First Posted Date: 2021-08-18

Last Posted Date: 2025-03-26

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 38

Registration Number: NCT05010564

Locations: 🇺🇸
Texas Children's Hospital, Houston, Texas, United States

Alternate Day Versus Daily Oral Iron Therapy in Adolescents

Phase 4

Completed

Conditions: Abnormal Uterine Bleeding
Iron Deficiency Anemia
Heavy Menstrual Bleeding

Interventions: Drug: Ferrous sulfate

First Posted Date: 2021-08-17

Last Posted Date: 2023-09-13

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 13

Registration Number: NCT05007899

Locations: 🇺🇸
Texas Children's Pavilion for Women, Houston, Texas, United States

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Phase 1

Recruiting

Conditions: Sarcoma
HER-2 Protein Overexpression
Osteosarcoma
Rhabdomyosarcoma
Ewing Sarcoma
Synovial Sarcoma
Soft Tissue Sarcoma
Undifferentiated Sarcoma

Interventions: Genetic: T cells or CAR T cells
Drug: Pembrolizumab Injectable Product
Drug: Nivolumab Injectable Product

First Posted Date: 2021-08-06

Last Posted Date: 2024-11-14

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 25

Registration Number: NCT04995003

Locations: 🇺🇸
Texas Children's Hospital, Houston, Texas, United States

Fit 24 Technology Intervention YOUTH

Not Applicable

Completed

Conditions: Diabetes Mellitus, Type 2

Interventions: Behavioral: Fit 24

First Posted Date: 2021-07-08

Last Posted Date: 2024-08-13

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 63

Registration Number: NCT04953442

Locations: 🇺🇸
Baylor College of Medicine, Houston, Texas, United States

Allogeneic CD30 Chimeric Antigen Receptor Epstein-Barr Virus-Specific T Lymphocytes in Relapsed or Refractory CD30-Positive Lymphomas

Phase 1

Withdrawn

Conditions: Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type
Classical Hodgkin Lymphoma

Interventions: Biological: CD30.CAR-EBVST cells

First Posted Date: 2021-07-07

Last Posted Date: 2023-09-07

Lead Sponsor: Baylor College of Medicine

Registration Number: NCT04952584

Locations: 🇺🇸
Texas Children's Hospital, Houston, Texas, United States
🇺🇸
Houston Methodist Hospital, Houston, Texas, United States

Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder

Not Applicable

Completed

Conditions: Obsessive-Compulsive Disorder in Children
Social Anxiety Disorder of Childhood
Obsessive-Compulsive Disorder in Adolescence
Separation Anxiety
Panic Disorder
Generalized Anxiety Disorder
Panic With Agoraphobia
Panic Attacks

Interventions: Behavioral: Bibliotherapy, low therapist contact SPACE
Behavioral: Standard SPACE

First Posted Date: 2021-06-10

Last Posted Date: 2025-03-04

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 68

Registration Number: NCT04922502

Locations: 🇺🇸
Baylor College of Medicine, Houston, Texas, United States

Monopolar Current Cutting Knife vs Bipolar RFA Knife

Not Applicable

Active, not recruiting

Conditions: Gastrointestinal Neoplasms

Interventions: Procedure: Endoscopic Submucosal Dissection
Procedure: Endoscopic Mucosal Resection

First Posted Date: 2021-06-09

Last Posted Date: 2025-02-14

Lead Sponsor: Baylor College of Medicine

Target Recruit Count: 80

Registration Number: NCT04919824

Locations: 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
🇺🇸
Baylor St. Lukes Medical Center (BSLMC), Houston, Texas, United States

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