BAYLOR COLLEGE OF MEDICINE

U-M's TOPMed Informatics Research Center receives $30M to enhance genetic data usability, focusing on heart, lung, blood, and sleep disorders, aiming to accelerate precision medicine research.

U-M's TOPMed Informatics Research Center receives $30M to enhance usability of genetic and genomic health data, aiming to advance precision medicine by making data more accessible and meaningful for researchers and healthcare providers worldwide.

Researchers at Baylor College of Medicine identified unique stool metabolites in women with endometriosis, including 4-hydroxyindole, which could lead to a non-invasive diagnostic test and a potential therapy. The study, published in the journal *Med*, also suggests a link between endometriosis and inflammatory bowel disease through shared microbiome profiles.

A study links endometriosis to the gut microbiome, identifying a lack of 4-hydroxyindole as a risk factor. This discovery could lead to early stool tests and microbiome-based treatments, potentially preventing the condition in lab mice.

Smith, dean of the Graduate School of Biomedical Sciences since 2019, continues as vice president of education affairs and professor of molecular and cellular biology. Her research focuses on estrogen receptors, gene expression regulation, tamoxifen resistance, and steroid hormone action. Smith values BCM's collaborative environment and looks forward to its research growth.

Dr. Asim Shah advises discussing politics calmly by listening, respecting boundaries, knowing when to stop, being respectful, mediating, taking breaks, and avoiding assumptions of correctness to prevent hostility during election season.

CellChorus, a Houston biotech company, received up to $2.5 million from NCATS for its TIMING platform, which uses AI and advanced microscopy for single-cell analysis. The funding supports label-free cell analysis via new AI and ML models, aiming to advance immuno-oncology therapies.

Pain, tingling, and cramps in legs/feet may signal poor blood circulation, leading to serious heart/health issues. Causes include atherosclerosis, high blood pressure, inflammation, blood clots, and genetic factors. Prevention involves lifestyle changes like quitting smoking, regular exercise, and maintaining a healthy weight. Medical interventions like balloon angioplasty or bypass may be needed if symptoms persist.

Pfizer funded COVID-19 vaccine ads omitted typical disclaimers about risks and FDA approval status, exploiting a loophole to present them as public service announcements. This allowed them to avoid required disclosures under Emergency Use Authorization, despite explicit warnings mandated for such ads.

Final results from the SWOG S1011 trial indicate no significant survival benefit from extended lymphadenectomy in localized muscle-invasive bladder cancer surgery, with increased risk of complications and death.