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Scios, Inc.
🇺🇸
United States
Country
🇺🇸
United States
Ownership
Subsidiary
Established
1981-01-01
Employees
509
Market Cap
-
Website
Clinical Trials
Related News
A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest
Phase 3
Completed
Conditions
Heart Failure, Congestive
Heart Decompensation
Interventions
Drug: nesiritide
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First Posted Date
2006-02-08
Last Posted Date
2011-06-10
Lead Sponsor
Scios, Inc.
Target Recruit Count
127
Registration Number
NCT00288730
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A Study to Develop Additional Safety and Clinical Experience With NATRECOR hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and Caliber of Blood Vessels
Phase 3
Completed
Conditions
Heart Failure, Congestive
Heart Decompensation
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First Posted Date
2006-01-02
Last Posted Date
2011-03-04
Lead Sponsor
Scios, Inc.
Target Recruit Count
305
Registration Number
NCT00271557
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A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy
Phase 3
Completed
Conditions
Cardiomyopathies
Heart Failure, Congestive
Dyspnea, Paroxysma
Interventions
Drug: Natrecor (nesiritide)
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First Posted Date
2005-12-26
Last Posted Date
2012-12-13
Lead Sponsor
Scios, Inc.
Target Recruit Count
250
Registration Number
NCT00270387
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FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hospitalization.
Phase 3
Completed
Conditions
Heart Failure, Congestive
Interventions
Drug: nesiritide
Drug: usual long term cardiac medications
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First Posted Date
2005-12-26
Last Posted Date
2011-07-26
Lead Sponsor
Scios, Inc.
Target Recruit Count
214
Registration Number
NCT00270361
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A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
Phase 3
Completed
Conditions
Symptomatic Decompensated Congestive Heart Failure
Congestive Heart Failure in Acute Coronary Syndrome
Interventions
Drug: nesiritide
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First Posted Date
2005-12-26
Last Posted Date
2011-06-10
Lead Sponsor
Scios, Inc.
Target Recruit Count
498
Registration Number
NCT00270374
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A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure
Phase 3
Completed
Conditions
Heart Failure, Congestive
Interventions
Drug: nesiritide
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First Posted Date
2005-12-26
Last Posted Date
2011-06-10
Lead Sponsor
Scios, Inc.
Target Recruit Count
255
Registration Number
NCT00270400
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SCIO-469: Open-Label Study for Patients With Myelodysplastic Syndromes.
Phase 2
Completed
Conditions
Bone Marrow Diseases
Myelodysplastic Syndromes
Hematologic Diseases
Bone Marrow Neoplasms
Interventions
Drug: SCIO-469
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First Posted Date
2005-06-13
Last Posted Date
2013-11-07
Lead Sponsor
Scios, Inc.
Target Recruit Count
62
Registration Number
NCT00113893
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Extension Study of the Efficacy and Safety of Oral SCIO-469 in Relapsed, Refractory Patients With Multiple Myeloma
Phase 2
Completed
Conditions
Multiple Myeloma
Interventions
Drug: SCIO-469
Drug: SCIO-469 and bortezomib
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First Posted Date
2004-11-08
Last Posted Date
2010-10-22
Lead Sponsor
Scios, Inc.
Target Recruit Count
30
Registration Number
NCT00095680
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A Study of the Safety and Efficacy of Follow-up Serial Infusions of Natrecor(Nesiritide) for the Management of Patients With Heart Failure
Phase 2
Completed
Conditions
Heart Failure, Congestive
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First Posted Date
2004-10-01
Last Posted Date
2011-05-20
Lead Sponsor
Scios, Inc.
Target Recruit Count
920
Registration Number
NCT00091520
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SPRiNG: SCIO-469 Patients With Rheumatoid Arthritis Not Receiving Methotrexate
Phase 2
Completed
Conditions
Arthritis, Rheumatoid
Interventions
Drug: Placebo
Drug: SCIO-469
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First Posted Date
2004-08-20
Last Posted Date
2010-10-18
Lead Sponsor
Scios, Inc.
Target Recruit Count
302
Registration Number
NCT00089921
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