MedPath

AstraZeneca

AstraZeneca logo
πŸ‡¬πŸ‡§United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

EXACOS EG Population

Not yet recruiting
Conditions
Chronic Obstructive Pulmonary Disease
First Posted Date
2025-05-21
Last Posted Date
2025-05-21
Lead Sponsor
AstraZeneca
Target Recruit Count
240
Registration Number
NCT06983340

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels

Phase 1
Not yet recruiting
Conditions
Healthy Participants
Interventions
Drug: AZD4954
Drug: Placebo
First Posted Date
2025-05-20
Last Posted Date
2025-05-20
Lead Sponsor
AstraZeneca
Target Recruit Count
120
Registration Number
NCT06980428
Locations
πŸ‡ΊπŸ‡Έ

Research Site, Brooklyn, Maryland, United States

A Study to Investigate the Effect of Food on Balcinrenone/Dapagliflozin Pharmacokinetics in Fed and Fasted State and Pharmacokinetics of Balcinrenone When Dosed With a P-gp Inhibitor in Healthy Participants.

Phase 1
Not yet recruiting
Conditions
Healthy Participants
Interventions
Drug: balcinrenone/ dapagliflozin
First Posted Date
2025-05-19
Last Posted Date
2025-05-19
Lead Sponsor
AstraZeneca
Target Recruit Count
14
Registration Number
NCT06979388
Locations
πŸ‡¬πŸ‡§

Research Site, Harrow, United Kingdom

A Study to Investigate the Pharmacokinetics of AZD2389 in Healthy Participants When Administered Alone and in Combination With Quinidine

Phase 1
Not yet recruiting
Conditions
Advanced Chronic Liver Disease
Healthy Participants
Interventions
First Posted Date
2025-05-16
Last Posted Date
2025-05-16
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT06974565
Locations
πŸ‡ΊπŸ‡Έ

Research Site, Brooklyn, Maryland, United States

ESPERANZA: T-DXd Pan-tumor ECA Study

Not yet recruiting
Conditions
Bladder Cancer
Biliary Tract Cancer
Cervical Cancer
Endometrial Cancer
Ovarian Cancer
Pancreatic Cancer
Colorectal Cancer
Lung Cancer
Other Tumors
First Posted Date
2025-05-15
Last Posted Date
2025-05-15
Lead Sponsor
AstraZeneca
Target Recruit Count
576
Registration Number
NCT06973161

A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants

Phase 1
Recruiting
Conditions
Advanced Chronic Liver Disease
Healthy Participants
Interventions
First Posted Date
2025-05-15
Last Posted Date
2025-05-18
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT06973005
Locations
πŸ‡ΊπŸ‡Έ

Research Site, Brooklyn, Maryland, United States

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Phase 3
Not yet recruiting
Conditions
Urinary Bladder Neoplasms
Immune Checkpoint Inhibitors
Methotrexate
Vinblastine
Doxorubicin
Cisplatin
Gemcitabine
Interventions
First Posted Date
2025-05-07
Last Posted Date
2025-05-07
Lead Sponsor
AstraZeneca
Target Recruit Count
150
Registration Number
NCT06960577
Locations
πŸ‡ͺπŸ‡Έ

Research Site, Santiago de Compostela, Spain

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Phase 3
Not yet recruiting
Conditions
Prostate Cancer
Interventions
Drug: Placebo
Drug: Androgen Deprivation Therapy (ADT)
Drug: Abiraterone + Prednisolone/Prednisone
First Posted Date
2025-05-01
Last Posted Date
2025-05-01
Lead Sponsor
AstraZeneca
Target Recruit Count
700
Registration Number
NCT06952803
Locations
πŸ‡ΉπŸ‡­

Research Site, Khon Kaen, Thailand

Tezspire Cardiac Events PASS

Not yet recruiting
Conditions
Cardiovascular Events
MACE
Interventions
First Posted Date
2025-04-30
Last Posted Date
2025-04-30
Lead Sponsor
AstraZeneca
Target Recruit Count
95574
Registration Number
NCT06951867

A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers

Phase 1
Not yet recruiting
Conditions
Healthy Participants
Interventions
Drug: AZD4916
Other: Placebo
First Posted Date
2025-04-30
Last Posted Date
2025-04-30
Lead Sponsor
AstraZeneca
Target Recruit Count
178
Registration Number
NCT06951880
Locations
πŸ‡¬πŸ‡§

Research Site, Harrow, United Kingdom

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