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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

Phase 3
Completed
Conditions
Recurrent or Metastatic PD-L1-positive or -Negative Squamous Cell Carcinoma of the Head and Neck SCCHN
Interventions
Drug: Standard of Care
Drug: MEDI4736 + Tremelimumab
First Posted Date
2015-02-24
Last Posted Date
2021-02-10
Lead Sponsor
AstraZeneca
Target Recruit Count
736
Registration Number
NCT02369874
Locations
🇺🇦

Research Site, Zaporizhzhia, Ukraine

T790M Mutation Positive 2nd Line STandard of cAre Registry

Withdrawn
Conditions
Non Small Cell Lung Cancer
First Posted Date
2015-02-23
Last Posted Date
2015-07-08
Lead Sponsor
AstraZeneca
Registration Number
NCT02368990
Locations
🇨🇳

Research Site, Taipei, Taiwan

A Phase I Study to Assess the Pharmacodynamics of Oral AR-C165395XX in Subjects With Type 2 Diabetes Mellitus (T2DM)

Phase 1
Completed
Conditions
Type 2 Diabetes Mellitus
Interventions
Other: Placebo
First Posted Date
2015-02-20
Last Posted Date
2016-06-23
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT02367066
Locations
🇺🇸

Research Site, Chula Vista, California, United States

Study in Healthy Subjects to Compare the Concentrations of the Omega-3 Fatty Acids EPA and DHA in Blood When Delivered as Three New Capsules in Relation to the Epanova® Capsule Under Fasting and Fed Conditions

Phase 1
Completed
Conditions
Pharmacokinetics
AUC
Relative Bioavailability
Cmax
Interventions
Drug: D1400147
Drug: D14000136
Drug: D14000137
Drug: Epanova®
First Posted Date
2015-02-09
Last Posted Date
2017-05-01
Lead Sponsor
AstraZeneca
Target Recruit Count
137
Registration Number
NCT02359045
Locations
🇺🇸

Research Site, Baltimore, Maryland, United States

Non-inteRvEntional Study to Observe rAtionaLe to Select add-on TherapY for Type 2 Diabetes Inadequately Controlled With Metformin.

Completed
Conditions
Type 2 Diabetes Mellitus
First Posted Date
2015-02-04
Last Posted Date
2017-05-30
Lead Sponsor
AstraZeneca
Target Recruit Count
1005
Registration Number
NCT02355145
Locations
🇧🇬

Research Site, Stara Zagora, Bulgaria

A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects.

Phase 2
Completed
Conditions
Non-alcoholic Fatty Liver Disease (NAFLD
Hypertriglyceridemia
Interventions
First Posted Date
2015-02-03
Last Posted Date
2018-09-25
Lead Sponsor
AstraZeneca
Target Recruit Count
78
Registration Number
NCT02354976
Locations
🇸🇪

Research Site, Uppsala, Sweden

A Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer

Phase 3
Completed
Conditions
Non - Small Cell Lung Cancer NSCLC
Interventions
Drug: MEDI4736 (durvalumab)
Drug: MEDI4736 (durvalumab) in combination with tremelimumab (anti-CTLA4)
First Posted Date
2015-02-02
Last Posted Date
2024-07-26
Lead Sponsor
AstraZeneca
Target Recruit Count
597
Registration Number
NCT02352948
Locations
🇬🇧

Research Site, Wolverhampton, United Kingdom

Autoinjector Device Assessment Study

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
Drug: Syringe with exenatide suspension
Drug: Auto-injector with exenatide suspension
First Posted Date
2015-01-29
Last Posted Date
2015-02-02
Lead Sponsor
AstraZeneca
Target Recruit Count
3052
Registration Number
NCT02349802
Locations
🇺🇸

Research Site, Lincoln, Nebraska, United States

Observational Multicenter Non-interventional Study on COPD Patients Treatment Strategies at the Time of Hospital Discharge and Within 12 Months of Follow-up on an Outpatient Primary Care Basement

Completed
Conditions
COPD
First Posted Date
2015-01-27
Last Posted Date
2017-12-22
Lead Sponsor
AstraZeneca
Target Recruit Count
1250
Registration Number
NCT02346292
Locations
🇷🇺

Research Site, Yaroslavl, Russian Federation

Phase Ib Study AZD1775 in Combination With Carboplatin and Paclitaxel in Adult Asian Patients With Solid Tumours

Phase 1
Completed
Conditions
Advanced Solid Tumours
Interventions
First Posted Date
2015-01-19
Last Posted Date
2019-03-25
Lead Sponsor
AstraZeneca
Target Recruit Count
19
Registration Number
NCT02341456
Locations
🇰🇷

Research Site, Seoul, Korea, Republic of

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