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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Phase 3
Completed
Conditions
Symptomatic Gastroesophageal Reflux Disease (sGERD)
Interventions
Drug: Matching placebo
First Posted Date
2008-02-29
Last Posted Date
2009-03-12
Lead Sponsor
AstraZeneca
Target Recruit Count
500
Registration Number
NCT00626535

Open, Randomized, Two Way Crossover Study Comparing the Effect of Esomeprazole Adminstered Orally and iv

Phase 4
Completed
Conditions
Gastroesophageal Reflux Disease
Interventions
First Posted Date
2008-02-29
Last Posted Date
2011-01-24
Lead Sponsor
AstraZeneca
Target Recruit Count
60
Registration Number
NCT00626262

A Randomized, Open-Label, Comparative 3-Way Treatment Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40mg, Lansoprazole 30mg, and Pantoprazole 40mg at Steady State in NSAID-Using Patients

Phase 4
Completed
Conditions
Heartburn
Upper Abdominal Pain
Nausea
Acid Regurgitation
Interventions
First Posted Date
2008-02-28
Last Posted Date
2008-02-28
Lead Sponsor
AstraZeneca
Target Recruit Count
100
Registration Number
NCT00625274

Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)

Phase 4
Completed
Conditions
Gastroesophageal Reflux Disease
Interventions
First Posted Date
2008-02-28
Last Posted Date
2011-01-24
Lead Sponsor
AstraZeneca
Target Recruit Count
60
Registration Number
NCT00625495

Atrial Fibrillation (AF) Patients Not Taking Vitamin-K Antagonist (VKA)

Phase 2
Completed
Conditions
Persistent or Permanent Non-valvular Atrial Fibrillation
First Posted Date
2008-02-26
Last Posted Date
2012-03-23
Lead Sponsor
AstraZeneca
Target Recruit Count
128
Registration Number
NCT00623779
Locations
🇬🇧

Research Site, Newcastle Upon Tyne, United Kingdom

Assessment of Endometrial Changes in Postmenopausal Women With Breast Cancer in Adjuvant Treatment With Anastrozole

Completed
Conditions
Breast Cancer
First Posted Date
2008-02-26
Last Posted Date
2009-03-09
Lead Sponsor
AstraZeneca
Target Recruit Count
165
Registration Number
NCT00623519
Locations
🇪🇸

Research Site, Sevilla, Spain

Post Marketing Surveillance Study of Byetta ™ (Exenatide) Use Among Filipino Patients

Completed
Conditions
Type 2 Diabetes Mellitus
First Posted Date
2008-02-25
Last Posted Date
2016-10-26
Lead Sponsor
AstraZeneca
Target Recruit Count
41
Registration Number
NCT00622323
Locations
🇵🇭

Research Site, Taytay, Philippines

Phase 1 PK Study of Cediranib in Single and Multiple Doses in Hepatically Impaired Patients With Solid Tumours

Phase 1
Completed
Conditions
Hepatic Impairment
Advanced Cancer
Interventions
First Posted Date
2008-02-22
Last Posted Date
2014-07-15
Lead Sponsor
AstraZeneca
Target Recruit Count
36
Registration Number
NCT00621725
Locations
🇳🇱

Research Site, Rotterdam, Netherlands

Phase I Safety and Tolerability Study of Cediranib (RECENTIN™, AZD2171) in Combination With Chemo in First Line Lung Cancer Patients

Phase 1
Completed
Conditions
Lung Cancer
Interventions
First Posted Date
2008-02-22
Last Posted Date
2012-12-17
Lead Sponsor
AstraZeneca
Target Recruit Count
62
Registration Number
NCT00621361
Locations
🇺🇸

Research Site, Houston, Texas, United States

Seroquel- Agitation Associated With Dementia

Phase 3
Completed
Conditions
Alzheimer's Disease
Vascular Dementia
Interventions
First Posted Date
2008-02-22
Last Posted Date
2009-03-25
Lead Sponsor
AstraZeneca
Target Recruit Count
333
Registration Number
NCT00621647
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