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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

Phase 2
Active, not recruiting
Conditions
Pulmonary Hypertension (World Health Organization Group 2)
Heart Failure
Interventions
Drug: Placebo
First Posted Date
2023-02-21
Last Posted Date
2025-05-13
Lead Sponsor
AstraZeneca
Target Recruit Count
260
Registration Number
NCT05737940
Locations
🇬🇧

Research Site, London, United Kingdom

Patient-Reported Outcomes of Benralizumab in Real-World Use in Severe Eosinophilic Asthma Patients in Taiwan (BEAT)

Completed
Conditions
Asthma
First Posted Date
2023-02-17
Last Posted Date
2025-03-07
Lead Sponsor
AstraZeneca
Target Recruit Count
43
Registration Number
NCT05734339
Locations
🇨🇳

Research Site, Taoyuan City, Taiwan

TEZSPIRE (Tezepelumab) Asthma Japan Post-Marketing Study (PMS)

Recruiting
Conditions
Bronchial Asthma (Only the Patients With Severe or Intractable Bronchial Asthma Which Could Not be Controlled With the Existing Therapy)
First Posted Date
2023-02-15
Last Posted Date
2025-05-01
Lead Sponsor
AstraZeneca
Target Recruit Count
400
Registration Number
NCT05729711
Locations
🇯🇵

Research Site, Yamanashi, Japan

Multiple Dose Study of Safety and Pharmacokinetics of MEDI0618 in Healthy Volunteers

Phase 1
Completed
Conditions
Chronic Pain
Interventions
Drug: Placebo
First Posted Date
2023-02-06
Last Posted Date
2024-01-05
Lead Sponsor
AstraZeneca
Target Recruit Count
36
Registration Number
NCT05714254
Locations
🇩🇪

Research Site, Berlin, Germany

eVusheld Assessment reaL wORld Effectiveness in Israel Clalit Health Services

Completed
Conditions
SARS-CoV-2
COVID-19
Interventions
First Posted Date
2023-02-03
Last Posted Date
2025-01-21
Lead Sponsor
AstraZeneca
Target Recruit Count
4000
Registration Number
NCT05712096
Locations
🇮🇱

Research Site, Ramat Gan, Israel

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Phase 2
Recruiting
Conditions
Gastric Cancer
Interventions
First Posted Date
2023-01-27
Last Posted Date
2025-04-11
Lead Sponsor
AstraZeneca
Target Recruit Count
240
Registration Number
NCT05702229
Locations
🇬🇧

Research Site, Oxford, United Kingdom

Effectiveness of the Oxford-AstraZeneca COVID-19 Vaccine as a 2nd Booster, the REFORCO-Brazil Study

Completed
Conditions
COVID-19
Interventions
Other: ChAdOx1 nCOV-19 vaccine (Vaxzeria)
Other: BNT162b2 (Pfizer)
Other: Ad26.COV2.S (Janssen)
Other: CoronaVac (Sinovac)
First Posted Date
2023-01-26
Last Posted Date
2024-11-21
Lead Sponsor
AstraZeneca
Target Recruit Count
188814085
Registration Number
NCT05697705
Locations
🇧🇷

Techtrials Pesquisa e Tecnologia Ltda., São Paulo, Brazil

A Study to Assess Safety, Tolerability, and Pharmacokinetics of AZD0186

Phase 1
Terminated
Conditions
Type 2 Diabetes
Interventions
Drug: Placebo
First Posted Date
2023-01-23
Last Posted Date
2024-12-13
Lead Sponsor
AstraZeneca
Target Recruit Count
31
Registration Number
NCT05694741
Locations
🇺🇸

Research Site, Glendale, California, United States

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

Phase 3
Recruiting
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2023-01-20
Last Posted Date
2025-05-21
Lead Sponsor
AstraZeneca
Target Recruit Count
200
Registration Number
NCT05692180
Locations
🇬🇧

Research Site, Manchester, United Kingdom

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations

First Posted Date
2023-01-18
Last Posted Date
2025-01-30
Lead Sponsor
AstraZeneca
Target Recruit Count
1350
Registration Number
NCT05687266
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

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