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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies

Phase 1
Completed
Conditions
Advanced Solid Malignancies
Interventions
First Posted Date
2022-10-10
Last Posted Date
2024-06-18
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT05573724
Locations
🇷🇴

Research Site, Cluj-Napoca, Romania

PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan

Recruiting
Conditions
Breast Neoplasms
Breast Cancer
Neoplasm Metastasis
First Posted Date
2022-10-10
Last Posted Date
2025-05-14
Lead Sponsor
AstraZeneca
Target Recruit Count
800
Registration Number
NCT05573893
Locations
🇩🇪

Research Site, Zittau, Germany

A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Phase 1
Completed
Conditions
Chronic Obstructive Pulmonary Disease
First Posted Date
2022-10-06
Last Posted Date
2025-04-29
Lead Sponsor
AstraZeneca
Target Recruit Count
108
Registration Number
NCT05569421
Locations
🇺🇸

Research Site, Glendale, California, United States

eVusheld Assessment reaL wORld Effectiveness in DoD Health System

Not yet recruiting
Conditions
COVID-19; SARS-CoV-2; 2019 Novel Coronavirus Disease
Interventions
First Posted Date
2022-10-06
Last Posted Date
2023-09-22
Lead Sponsor
AstraZeneca
Target Recruit Count
6000
Registration Number
NCT05569408
Locations
🇺🇸

Research Site, Bethesda, Maryland, United States

Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Liver Disease

Phase 1
Completed
Conditions
NAFLD
Nonalcoholic Fatty Liver Disease
Nonalcoholic Steatohepatitis
NASH
Non-alcoholic Fatty Liver Disease
Fatty Liver, Nonalcoholic
Interventions
Drug: AZD7503 Intervention
First Posted Date
2022-09-29
Last Posted Date
2024-03-18
Lead Sponsor
AstraZeneca
Target Recruit Count
19
Registration Number
NCT05560607
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

Study of Durvalumab Plus Tremelimumab as First-line Treatment in Chinese Patients With Unresectable Hepatocellular Carinoma

Phase 3
Recruiting
Conditions
Hepatocellular Carcinoma
Interventions
First Posted Date
2022-09-28
Last Posted Date
2025-02-07
Lead Sponsor
AstraZeneca
Target Recruit Count
210
Registration Number
NCT05557838
Locations
🇨🇳

Research Site, Zhengzhou, China

Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom

Recruiting
Conditions
Chronic Lymphocytic Leukemia, CLL
Interventions
First Posted Date
2022-09-28
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
350
Registration Number
NCT05557695
Locations
🇬🇧

Research Site, Wigan, United Kingdom

PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction

Phase 3
Completed
Conditions
Asthma
Interventions
Combination Product: PT027
Combination Product: PT007
First Posted Date
2022-09-26
Last Posted Date
2025-01-08
Lead Sponsor
AstraZeneca
Target Recruit Count
21
Registration Number
NCT05555290
Locations
🇺🇸

Research Site, Columbia, Maryland, United States

A Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With Itraconazole

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
First Posted Date
2022-09-23
Last Posted Date
2023-01-06
Lead Sponsor
AstraZeneca
Target Recruit Count
14
Registration Number
NCT05551897
Locations
🇬🇧

Research Site, Harrow, United Kingdom

BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging

Phase 4
Completed
Conditions
Asthma
Interventions
Combination Product: Benralizumab
First Posted Date
2022-09-23
Last Posted Date
2025-03-25
Lead Sponsor
AstraZeneca
Target Recruit Count
45
Registration Number
NCT05552508
Locations
🇬🇧

Research Site, Nottingham, United Kingdom

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