MedPath

AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

Phase 3
Recruiting
Conditions
HER2-positive Gastric Cancer
Gastroesophageal Junction Adenocarcinoma
Interventions
First Posted Date
2025-01-09
Last Posted Date
2025-04-27
Lead Sponsor
AstraZeneca
Target Recruit Count
840
Registration Number
NCT06764875
Locations
🇻🇳

Research Site, Vinh, Vietnam

A Phase IIIB Study to Evaluate the Use of Capivasertib in Combination With Fulvestrant in Patients With Advanced Breast Cancer Who Have Relapsed/Progressed on ET and CDK4/6 Inhibitor Reflecting Real World Clinical Practice in Spain

Phase 3
Recruiting
Conditions
Locally Advanced or Metastatic Breast Cancer
Interventions
First Posted Date
2025-01-08
Last Posted Date
2025-05-13
Lead Sponsor
AstraZeneca
Target Recruit Count
100
Registration Number
NCT06764186
Locations
🇪🇸

Research Site, Zaragoza, Spain

Clinical and Demographic Features of Patients With Moderate to Severe Active Systemic Lupus Erythematosus in Russia

Recruiting
Conditions
Systemic Lupus Erythematosus
First Posted Date
2025-01-06
Last Posted Date
2025-05-18
Lead Sponsor
AstraZeneca
Target Recruit Count
600
Registration Number
NCT06759519
Locations
🇷🇺

Research Site, Yaroslavl, Russian Federation

Human ADME Study of [14C]-Ceralasertib (AZD6738) and Absolute Bioavailability of Ceralasertib

Phase 1
Not yet recruiting
Conditions
Neoplasm
Interventions
Drug: [14C] AZD6738
First Posted Date
2025-01-01
Last Posted Date
2025-01-01
Lead Sponsor
AstraZeneca
Target Recruit Count
8
Registration Number
NCT06754761
Locations
🇬🇧

Research Site, London, United Kingdom

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Phase 1
Recruiting
Conditions
Staphylococcus Aureus
Interventions
Other: Placebo
First Posted Date
2024-12-27
Last Posted Date
2025-04-24
Lead Sponsor
AstraZeneca
Target Recruit Count
231
Registration Number
NCT06749457
Locations
🇺🇸

Research Site, Beaumont, Texas, United States

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

Phase 3
Recruiting
Conditions
Eosinophilic Asthma
First Posted Date
2024-12-27
Last Posted Date
2025-05-01
Lead Sponsor
AstraZeneca
Target Recruit Count
400
Registration Number
NCT06750289
Locations
🇬🇧

Research Site, Portsmouth, United Kingdom

A Study to Evaluate the Safety, Tolerability, PK, and PD Effects of AZD2389 in Participants With Liver Fibrosis and Compensated Cirrhosis.

Phase 2
Recruiting
Conditions
Liver Fibrosis
Hepatic Cirrhosis
Interventions
First Posted Date
2024-12-27
Last Posted Date
2025-05-15
Lead Sponsor
AstraZeneca
Target Recruit Count
36
Registration Number
NCT06750276
Locations
🇬🇧

Research Site, London, United Kingdom

A Study to Evaluate the Use of Durvalumab in Combination With Platinum-based Chemotherapy Followed by Durvalumab With Olaparib as First-line Treatment in Advanced or Recurrent Endometrial Cancer in Spain

Phase 3
Recruiting
Conditions
Advanced or Recurrent Endometrial Cancer
Interventions
First Posted Date
2024-12-24
Last Posted Date
2025-05-07
Lead Sponsor
AstraZeneca
Target Recruit Count
85
Registration Number
NCT06746116
Locations
🇪🇸

Research Site, Zaragoza, Spain

A Comparative Effectiveness Study of Mortality Outcomes and Related Cardiopulmonary Events Among a Cohort of Chronic Obstructive Pulmonary Disease (COPD) Patients Who Initiate Breztri and Multiple Inhaler Triple Therapy (MITT) in the United States (US)

Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: MITT
First Posted Date
2024-12-20
Last Posted Date
2024-12-20
Lead Sponsor
AstraZeneca
Target Recruit Count
22369
Registration Number
NCT06744374
Locations
🇺🇸

AstraZeneca, Wilmington, Delaware, United States

Prospective Observational Multicenter Study of Patients With AH and CKD Markers in Kazakhstan (PROGRESS-CKD)

Recruiting
Conditions
Rate of CKD Diagnosis in Patients With AH and CKD Markers
Demographic and Clinical Characteristics for Those Patients
Routine Therapy Before and After the Diagnosis of CKD
First Posted Date
2024-12-20
Last Posted Date
2025-02-05
Lead Sponsor
AstraZeneca
Target Recruit Count
1282
Registration Number
NCT06744335
Locations
🇰🇿

Research Site, Temirlanovka Village, Kazakhstan

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