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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Phase 3
Active, not recruiting
Conditions
Locally Advanced (Inoperable) or Metastatic Breast Cancer
Interventions
First Posted Date
2020-03-12
Last Posted Date
2023-05-30
Lead Sponsor
AstraZeneca
Target Recruit Count
818
Registration Number
NCT04305496
Locations
🇬🇧

Research Site, Sutton, United Kingdom

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma

Phase 3
Completed
Conditions
Severe Uncontrolled Asthma
Interventions
First Posted Date
2020-03-12
Last Posted Date
2023-05-18
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT04305405
Locations
🇯🇵

Research Site, Zentsuji-shi, Japan

Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease.

Phase 3
Withdrawn
Conditions
Sickle Cell Disease
Interventions
Drug: Placebo
First Posted Date
2020-03-03
Last Posted Date
2020-07-15
Lead Sponsor
AstraZeneca
Registration Number
NCT04293172

Open-label Extension Study of Brazikumab in Ulcerative Colitis

Phase 2
Terminated
Conditions
Ulcerative Colitis
Interventions
First Posted Date
2020-02-20
Last Posted Date
2023-11-09
Lead Sponsor
AstraZeneca
Target Recruit Count
57
Registration Number
NCT04277546
Locations
🇨🇳

Research Site, Taipei, Taiwan

ChAracterisation of ItaliaN Severe Uncontrolled Asthmatic patieNts Key Features When Receiving Benralizumab

Completed
Conditions
Severe Asthma
First Posted Date
2020-02-17
Last Posted Date
2023-08-31
Lead Sponsor
AstraZeneca
Target Recruit Count
217
Registration Number
NCT04272463
Locations
🇮🇹

Research Site, Verona, Italy

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

First Posted Date
2020-02-13
Last Posted Date
2025-02-11
Lead Sponsor
AstraZeneca
Target Recruit Count
813
Registration Number
NCT04269200
Locations
🇪🇸

Research Site, Mallorca, Spain

A First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD2373 After Single Dose Administration in Healthy Male Subjects of African Ancestry.

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: AZD2373 subcutaneous injection
Drug: Placebo
First Posted Date
2020-02-13
Last Posted Date
2023-07-10
Lead Sponsor
AstraZeneca
Target Recruit Count
30
Registration Number
NCT04269031
Locations
🇺🇸

Research Site, Brooklyn, Maryland, United States

A Study to Assess the Effect of Verinurad on the Electric Activity of the Heart

Phase 1
Completed
Conditions
Healthy Volunteers (Intended Indication: Chronic Kidney Disease)
Interventions
First Posted Date
2020-02-05
Last Posted Date
2022-01-31
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT04256629
Locations
🇩🇪

Research Site, Berlin, Germany

Study of Durvalumab Following Radiation Therapy in Patients With Stage 3 Unresectable NSCLC Ineligible for Chemotherapy

Phase 2
Completed
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2020-01-30
Last Posted Date
2025-01-10
Lead Sponsor
AstraZeneca
Target Recruit Count
102
Registration Number
NCT04249362
Locations
🇪🇸

Research Site, Sabadell(Barcelona), Spain

A Study to Evaluate the Effectiveness and Tolerability of a Second Maintenance Treatment in Participants With Ovarian Cancer, Who Have Previously Received Polyadenosine 5'Diphosphoribose [Poly (ADP Ribose)] Polymerase Inhibitor (PARPi) Treatment.

Phase 2
Withdrawn
Conditions
Ovarian Cancer
Interventions
Drug: Placebo to match olaparib
First Posted Date
2020-01-23
Last Posted Date
2021-03-10
Lead Sponsor
AstraZeneca
Registration Number
NCT04239014
Locations
🇪🇸

Research Site, Barcelona, Spain

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