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AstraZeneca

AstraZeneca logo
🇬🇧United Kingdom
Ownership
Public
Employees
89.9K
Market Cap
$270.3B
Website
http://www.astrazeneca.co.uk
Introduction

AstraZeneca Plc is a holding company, which engages in the research, development, manufacture, and commercialization of prescription medicines. The company was founded on June 17, 1992 and is headquartered in Cambridge, the United Kingdom.

A Study to Reveal the Patient Characteristics and Treatment Patterns of Stage III Non-small-cell Lung Cancer Patients

Completed
Conditions
Non-small-cell Lung Cancer (NSCLC)
First Posted Date
2018-10-31
Last Posted Date
2020-10-05
Lead Sponsor
AstraZeneca
Target Recruit Count
3111
Registration Number
NCT03725475
Locations
🇺🇾

Research Site, Montevideo, Uruguay

Evaluation in Real World of Molecular Testing and Treatment Patterns for EGFR Mutation in Lung Cancer Patients

Completed
Conditions
Carcinoma, Non-Small-Cell Lung
First Posted Date
2018-10-26
Last Posted Date
2019-06-12
Lead Sponsor
AstraZeneca
Target Recruit Count
463
Registration Number
NCT03721289
Locations
🇺🇾

Research Site, Montevideo, Uruguay

AZD4635 Relative Bioavailability Study

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: AZD4635 solid oral formulation - fasted
Drug: AZD4635 50 mg nano-suspension (reference)
Drug: AZD4635 solid oral formulation - fed
Drug: AZD4635 solid oral formulation variant 1 - fasted
Drug: AZD4635 solid oral formulation variant 2 - fasted
Drug: [14C] AZD4635 IV microtracer - fasted
First Posted Date
2018-10-18
Last Posted Date
2020-05-07
Lead Sponsor
AstraZeneca
Target Recruit Count
21
Registration Number
NCT03710434
Locations
🇬🇧

Research Site, Ruddington, United Kingdom

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

Phase 3
Active, not recruiting
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
Other: Placebo
First Posted Date
2018-10-16
Last Posted Date
2025-04-17
Lead Sponsor
AstraZeneca
Target Recruit Count
407
Registration Number
NCT03706690
Locations
🇹🇷

Research Site, Malatya, Turkey

Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma

Phase 3
Completed
Conditions
Asthma
Interventions
Biological: Tezepelumab
Other: Placebo
First Posted Date
2018-10-15
Last Posted Date
2023-06-06
Lead Sponsor
AstraZeneca
Target Recruit Count
951
Registration Number
NCT03706079
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Limited Stage Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation Therapy

Phase 3
Active, not recruiting
Conditions
Small Cell Lung Cancer
Interventions
First Posted Date
2018-10-11
Last Posted Date
2025-02-11
Lead Sponsor
AstraZeneca
Target Recruit Count
730
Registration Number
NCT03703297
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

Characteristics of Patients With Type 2 Diabetes Mellitus (CVD-RNDR)

Completed
Conditions
Type 2 Diabetes
First Posted Date
2018-10-03
Last Posted Date
2019-06-10
Lead Sponsor
AstraZeneca
Target Recruit Count
10000
Registration Number
NCT03694470
Locations
🇷🇺

Research site, Moscow, Russian Federation

A Study to Determine Safety of Durvalumab After Sequential Chemo Radiation in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
First Posted Date
2018-10-02
Last Posted Date
2024-06-18
Lead Sponsor
AstraZeneca
Target Recruit Count
117
Registration Number
NCT03693300
Locations
🇬🇧

Research Site, Stoke on Trent, United Kingdom

Study to Evaluate Tezepelumab on Airway Inflammation in Adults With Uncontrolled Asthma (CASCADE)

Phase 2
Completed
Conditions
Lung Diseases, Obstructive
Immune System Diseases
Lung Diseases
Respiratory Tract Diseases
Hypersensitivity, Immediate
Hypersensitivity
Asthma
Bronchial Diseases
Respiratory Hypersensitivity
Interventions
Biological: Tezepelumab
Other: Placebo
First Posted Date
2018-09-28
Last Posted Date
2022-02-21
Lead Sponsor
AstraZeneca
Target Recruit Count
116
Registration Number
NCT03688074
Locations
🇬🇧

Research Site, Wythenshawe, United Kingdom

Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer

Phase 3
Active, not recruiting
Conditions
Unresectable Locally Advanced Urothelial Cancer
Metastatic Urothelial Cancer
Interventions
First Posted Date
2018-09-24
Last Posted Date
2025-02-06
Lead Sponsor
AstraZeneca
Target Recruit Count
1246
Registration Number
NCT03682068
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

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