FRED HUTCHINSON CANCER CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Employees: -

Market Cap: -

Website: https://www.fredhutch.org

Clinical Trials

Vaccine Responsiveness After CAR-T Cell Therapy

Phase 1

Active, not recruiting

Conditions: B-Cell Neoplasm

Interventions: Biological: Wistar Rabies Virus Strain PM-1503-3M Vaccine
Procedure: Biospecimen Collection

First Posted Date: 2020-06-01

Last Posted Date: 2025-03-24

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 49

Registration Number: NCT04410900

Locations: 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Quit2Heal Smartphone App in Helping Cancer Patients Quit Smoking

Phase 3

Active, not recruiting

Conditions: Malignant Solid Neoplasm
Hematopoietic and Lymphoid System Neoplasm

Interventions: Behavioral: Quit2Heal
Behavioral: QuitGuide
Other: Survey Administration

First Posted Date: 2020-06-01

Last Posted Date: 2025-02-04

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 427

Registration Number: NCT04409236

Locations: 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis

Phase 2

Recruiting

Conditions: Secondary Myelofibrosis
Primary Myelofibrosis

Interventions: Procedure: Allogeneic Hematopoietic Stem Cell Transplantation
Drug: Busulfan
Drug: Cyclophosphamide
Drug: Fludarabine
Drug: Melphalan
Drug: Methotrexate
Drug: Mycophenolate Mofetil
Drug: Ruxolitinib
Drug: Tacrolimus
Radiation: Total-Body Irradiation
Procedure: Computed Tomography
Procedure: Echocardiography
Procedure: Bone Marrow Aspiration and Biopsy
Procedure: Magnetic Resonance Imaging
Procedure: Ultrasound Imaging

First Posted Date: 2020-05-12

Last Posted Date: 2025-02-26

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 60

Registration Number: NCT04384692

Locations: 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Phase 1

Recruiting

Conditions: Recurrent Chronic Myelomonocytic Leukemia
Recurrent Myelodysplastic Syndrome
Refractory Acute Myeloid Leukemia
Refractory Chronic Myelomonocytic Leukemia
Refractory Mixed Phenotype Acute Leukemia
Recurrent Acute Myeloid Leukemia
Refractory Myelodysplastic Syndrome
Refractory Acute Leukemia of Ambiguous Lineage
Refractory Acute Undifferentiated Leukemia

Interventions: Drug: Cyclophosphamide
Drug: Cladribine
Drug: Cyclosporine
Drug: Cytarabine
Drug: Mycophenolate Sodium
Biological: Filgrastim
Procedure: Hematopoietic Cell Transplantation
Drug: Mitoxantrone
Drug: Idarubicin
Drug: Mycophenolate Mofetil
Drug: Fludarabine
Radiation: Total-Body Irradiation
Procedure: Multigated Acquisition Scan
Procedure: Echocardiography
Procedure: X-Ray Imaging
Procedure: Bone Marrow Biopsy
Procedure: Bone Marrow Aspiration
Procedure: Biospecimen Collection

First Posted Date: 2020-05-05

Last Posted Date: 2025-02-20

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 120

Registration Number: NCT04375631

Locations: 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

Phase 2

Recruiting

Conditions: Primary Myelofibrosis
Secondary Myelofibrosis

Interventions: Drug: Cyclophosphamide
Drug: JAK Inhibitor
Drug: Fludarabine
Biological: Recombinant Granulocyte Colony-Stimulating Factor
Drug: Melphalan
Drug: Mycophenolate Mofetil
Procedure: Peripheral Blood Stem Cell Transplantation
Drug: Tacrolimus
Radiation: Total-Body Irradiation
Procedure: Computed Tomography
Procedure: Magnetic Resonance Imaging
Procedure: Bone Marrow Biopsy
Procedure: Bone Marrow Aspiration
Procedure: Biospecimen Collection
Procedure: Echocardiography
Procedure: Multigated Acquisition Scan

First Posted Date: 2020-04-30

Last Posted Date: 2025-04-08

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 20

Registration Number: NCT04370301

Locations: 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy

Phase 2

Completed

Conditions: B-Cell Non-Hodgkin Lymphoma

Interventions: Biological: Anakinra
Procedure: X-Ray Imaging
Procedure: Positron Emission Tomography
Procedure: Computed Tomography
Procedure: Bone Marrow Aspiration
Procedure: Bone Marrow Biopsy
Procedure: Lumbar Puncture
Procedure: Biospecimen Collection

First Posted Date: 2020-04-24

Last Posted Date: 2025-01-07

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 27

Registration Number: NCT04359784

Locations: 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

An Innovative Conversational Agent (Quitbot) for Smoking Cessation

Phase 3

Active, not recruiting

Conditions: Cigarette Smoking-Related Carcinoma

Interventions: Other: Control Smoking Cessation Program
Other: Experimental Smoking Cessation Program

First Posted Date: 2020-03-16

Last Posted Date: 2024-10-21

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 1647

Registration Number: NCT04308759

Locations: 🇺🇸
Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Establishing Optimal Number of Doses for HPV Vaccination in Children and Adolescents Living With HIV, OPTIMO Trial

Phase 4

Active, not recruiting

Conditions: HIV Infection

Interventions: Biological: Recombinant Human Papillomavirus Nonavalent Vaccine

First Posted Date: 2020-02-12

Last Posted Date: 2025-03-21

Lead Sponsor: Fred Hutchinson Cancer Center

Target Recruit Count: 97

Registration Number: NCT04265950

Locations: 🇵🇪
Via Libre, Lima, Peru
🇧🇷
Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation (FIOCRUZ) STD and AIDS Clinical Research Laboratory, Rio de Janeiro, RJ, Brazil
🇭🇹
GHESKIO Center, Port-au-Prince, Haiti