Exelixis

Exelixis logo
🇺🇸United States
Ownership
Public
Established
1994-01-01
Employees
1.3K
Market Cap
$7.3B
Website
http://www.exelixis.com
Introduction

Exelixis, Inc. operates as an oncology company, which focuses on discovering, developing, and commercialization of new medicines for difficult-to-treat cancers. Its products include cabometyx, cometriq, and cotellic. The company was founded by Stelios Papadopoulos on November 15, 1994, and is headquartered in Alameda, CA.

A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma

First Posted Date
2013-05-31
Last Posted Date
2021-04-27
Lead Sponsor
Exelixis
Target Recruit Count
658
Registration Number
NCT01865747

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-01-07
Last Posted Date
2014-09-22
Lead Sponsor
Exelixis
Target Recruit Count
32
Registration Number
NCT01761773

Expanded Access of Cabozantinib in Medullary Thyroid Cancer

First Posted Date
2012-09-11
Last Posted Date
2013-01-16
Lead Sponsor
Exelixis
Registration Number
NCT01683110

Dose-Finding Study of Cabozantinib (XL184) in Japanese Subjects With Advanced Cancer

First Posted Date
2012-03-14
Last Posted Date
2015-08-20
Lead Sponsor
Exelixis
Target Recruit Count
85
Registration Number
NCT01553656
Locations
🇯🇵

National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

🇯🇵

The Cancer Institute Hospital of the Japanese Foundation for Cancer Research (JFCR), Ariake, Koto, Japan

Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-12-16
Last Posted Date
2014-09-22
Lead Sponsor
Exelixis
Target Recruit Count
26
Registration Number
NCT01493869
Locations
🇺🇸

McGuire VA Medical Center, Richmond, Virginia, United States

A Drug-Drug Interaction Study of the Effects of XL184 (Cabozantinib) on Rosiglitazone in Subjects With Solid Tumors

First Posted Date
2010-04-09
Last Posted Date
2013-09-19
Lead Sponsor
Exelixis
Target Recruit Count
40
Registration Number
NCT01100619
Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

🇺🇸

The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States

🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

and more 2 locations

Study of Multiple Doses and Regimens of XL184 (Cabozantinib) in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-02-15
Last Posted Date
2014-07-30
Lead Sponsor
Exelixis
Target Recruit Count
19
Registration Number
NCT01068782

Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma

First Posted Date
2009-08-17
Last Posted Date
2014-09-22
Lead Sponsor
Exelixis
Target Recruit Count
26
Registration Number
NCT00960492
Locations
🇺🇸

University of Virginia Health System/Division of Neuro-Oncology, Charlottesville, Virginia, United States

🇺🇸

Duke University Medical Center; The Preston Robert Tisch Brain Tumor Center, Durham, North Carolina, United States

🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

and more 5 locations
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