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Alaunos Therapeutics

Alaunos Therapeutics logo
🇺🇸United States
Ownership
Public
Employees
1
Market Cap
$4.4M
Website
http://www.alaunos.com
Introduction

ZIOPHARM Oncology, Inc. is a biopharmaceutical company, which engages in the development, acquisition, and commercialization of immuno-oncology platforms that leverage cell- and gene-based therapies to treat patients with cancer. Its pipeline includes Sleeping Beauty TCR-T Targeting neoantigens; Ad-RTS-hlL-12 + veledimex; and Sleeping Beauty CAR-T. The company was founded on September 9, 2003 and is headquartered in Boston, MA.

Clinical Trials

37

Active:2
Completed:18

Trial Phases

3 Phases

Phase 1:27
Phase 2:6
Phase 3:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (35 trials with phase data)• Click on a phase to view related trials

Phase 1
27 (77.1%)
Phase 2
6 (17.1%)
Phase 3
2 (5.7%)

Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs

Active, not recruiting
Conditions
Colorectal Cancer
Pancreatic Cancer
Non-small Cell Lung Cancer
Ovarian Cancer
Adenocarcinoma of Lung
Adenosquamous Cell Lung Cancer
Ovary Neoplasm
Cholangiocarcinoma
Gynecologic Cancer
Squamous Cell Lung Cancer
First Posted Date
2022-03-23
Last Posted Date
2024-05-29
Lead Sponsor
Alaunos Therapeutics
Target Recruit Count
8
Registration Number
NCT05292859
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors

Phase 1
Active, not recruiting
Conditions
Ovary Neoplasm
Adenosquamous Cell Lung Cancer
Cholangiocarcinoma
Adenocarcinoma of Lung
Colorectal Cancer
Pancreatic Cancer
Ovarian Cancer
Endometrial Cancer
Non-small Cell Lung Cancer
Ovarian Carcinoma
First Posted Date
2022-01-18
Last Posted Date
2024-05-29
Lead Sponsor
Alaunos Therapeutics
Target Recruit Count
180
Registration Number
NCT05194735
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors

Suspended
Conditions
Colo-rectal Cancer
Endometrial Cancer
Pancreas Cancer
Ovarian Cancer
Cholangiocarcinoma
Non-small Cell Lung Cancer
First Posted Date
2021-11-18
Last Posted Date
2024-05-29
Lead Sponsor
Alaunos Therapeutics
Target Recruit Count
2000
Registration Number
NCT05124743
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma

Phase 2
Terminated
Conditions
Glioblastoma
Interventions
First Posted Date
2019-07-02
Last Posted Date
2025-04-18
Lead Sponsor
Alaunos Therapeutics
Target Recruit Count
40
Registration Number
NCT04006119
Locations
🇺🇸

Cedars Sinai, Los Angeles, California, United States

🇺🇸

University of California - San Francisco, San Francisco, California, United States

🇺🇸

Baptist MD Anderson Cancer Center, Jacksonville, Florida, United States

and more 4 locations

Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102

Phase 1
Completed
Conditions
Glioblastoma
Interventions
Biological: Ad-RTS-hIL-12
First Posted Date
2018-09-20
Last Posted Date
2021-09-22
Lead Sponsor
Alaunos Therapeutics
Target Recruit Count
36
Registration Number
NCT03679754
Locations
🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

Northwestern Memorial Hospital, Chicago, Illinois, United States

🇺🇸

NYU - Langone Health, New York, New York, United States

and more 1 locations
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