Syndax Pharmaceuticals

🇺🇸United States
Ownership
-
Employees
184
Market Cap
$1.7B
Website
Introduction

Syndax Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company engaged in the development of cancer therapies. Its product candidates include SNDX-5613 and SNDX-6352. The company was founded by Richard A. Heyman, Eckard Weber, Peter Ordentlich, Ronald M. Evans and Michael Downes on October 11, 2005 and is headquartered in Waltham, MA.

A Study of SNDX-5613 in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias

First Posted Date
2024-01-26
Last Posted Date
2024-12-17
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
76
Registration Number
NCT06226571
Locations
🇺🇸

Emory Winship Cancer Institute, Atlanta, Georgia, United States

🇺🇸

MUSC Hollings Cancer Center (HCC), Charleston, South Carolina, United States

🇺🇸

LDS Hospital - Intermountain Healthcare, Salt Lake City, Utah, United States

and more 7 locations

MAXPIRe: Study to Evaluate Axatilimab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-11-15
Last Posted Date
2024-12-17
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
135
Registration Number
NCT06132256
Locations
🇦🇺

Mackay Hospital & Health Service, West Mackay, Queensland, Australia

🇧🇪

OLV Hospital Aalst, Aalst, Oost-Vlaanderen, Belgium

🇧🇪

AZ Groeninge, Kortrijk, West-Vlaanderen, Belgium

and more 36 locations

Expanded Access Program for Revumenib

First Posted Date
2023-06-26
Last Posted Date
2024-12-17
Lead Sponsor
Syndax Pharmaceuticals
Registration Number
NCT05918913
Locations
🇺🇸

City of Hope at Orange County Lennar Foundation Cancer Center, Irvine, California, United States

🇺🇸

Advent Health Orlando, Orlando, Florida, United States

🇺🇸

Lurie Children's Hospital of Chicago, Chicago, Illinois, United States

and more 30 locations

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2023-02-16
Last Posted Date
2024-12-18
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
42
Registration Number
NCT05731947
Locations
🇺🇸

Honor Health Research Institute, Scottsdale, Arizona, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, Manhattan, New York, United States

and more 3 locations

Study of Radiolabeled Revumenib in Adults With Acute Leukemia

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2022-06-07
Last Posted Date
2024-10-23
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
8
Registration Number
NCT05406817
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

First Posted Date
2022-04-13
Last Posted Date
2024-08-13
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT05326516
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

University of California, San Francisco (UCSF) Benioff Children's Hospital, San Francisco, California, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 8 locations

A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2021-01-14
Last Posted Date
2024-10-10
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
241
Registration Number
NCT04710576
Locations
🇺🇸

The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

🇺🇸

University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh, Pennsylvania, United States

🇨🇦

Princess Margaret Hospital, Toronto, Ontario, Canada

and more 117 locations

A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19

First Posted Date
2020-06-04
Last Posted Date
2022-07-22
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
1
Registration Number
NCT04415073
Locations
🇺🇸

HonorHealth, Scottsdale, Arizona, United States

🇺🇸

Montefiore Medical Center, Bronx, New York, United States

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

First Posted Date
2019-08-22
Last Posted Date
2024-11-21
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
413
Registration Number
NCT04065399
Locations
🇫🇷

Hospital Saint-Louis - APHP, Paris, France

🇫🇷

Centre Hospitalier Universitaire (CHU) de Bordeaux, Pessac, France

🇩🇪

University Hospital Of Ulm, Universitatsklinikum Ulm, Ulm, Baden-Württemberg, Germany

and more 54 locations

A Phase 1/2 Study to Evaluate Axatilimab in Participants With Active cGVHD

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2018-07-27
Last Posted Date
2024-11-27
Lead Sponsor
Syndax Pharmaceuticals
Target Recruit Count
41
Registration Number
NCT03604692
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

University of Minnesota Medical Center, Minneapolis, Minnesota, United States

🇺🇸

University of Miami Miller School of Medicine, Miami, Florida, United States

and more 8 locations
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