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Symphogen A/S

Symphogen A/S logo
🇩🇰Denmark
Ownership
Subsidiary
Established
2000-01-01
Employees
101
Market Cap
-
Website
http://www.symphogen.com

Clinical Trials

33

Active:17
Completed:10

Trial Phases

3 Phases

Phase 1:23
Phase 2:5
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (29 trials with phase data)• Click on a phase to view related trials

Phase 1
23 (79.3%)
Phase 2
5 (17.2%)
Phase 3
1 (3.4%)

Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies

Phase 1
Completed
Conditions
Solid Tumor
Metastatic Cancer
Interventions
First Posted Date
2020-12-17
Last Posted Date
2024-12-09
Lead Sponsor
Symphogen A/S
Target Recruit Count
48
Registration Number
NCT04672434
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

NEXT Oncology, San Antonio, Texas, United States

and more 1 locations

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Phase 1
Completed
Conditions
Metastatic Cancer
Solid Tumor
Interventions
First Posted Date
2020-11-24
Last Posted Date
2024-06-26
Lead Sponsor
Symphogen A/S
Target Recruit Count
78
Registration Number
NCT04641871
Locations
🇺🇸

University of Colorado, Aurora, Colorado, United States

🇺🇸

Mayo Clinic - Jacksonville, Jacksonville, Florida, United States

🇺🇸

Moffitt Cancer Center, Tampa, Florida, United States

and more 14 locations

Sym004 Versus TAS-102 in Patients With mCRC

Phase 3
Withdrawn
Conditions
Metastatic Colorectal Cancer
Colorectal Cancer Metastatic
Carcinoma
Interventions
First Posted Date
2018-10-23
Last Posted Date
2019-02-04
Lead Sponsor
Symphogen A/S
Registration Number
NCT03717038

Sym004 Versus Futuximab or Modotuximab in Patients With mCRC

Phase 2
Terminated
Conditions
Colorectal Cancer Metastatic
Metastatic Colorectal Cancer
Carcinoma
Interventions
First Posted Date
2018-06-08
Last Posted Date
2020-09-28
Lead Sponsor
Symphogen A/S
Target Recruit Count
2
Registration Number
NCT03549338
Locations
🇺🇸

City of Hope - Comprehensive Cancer Center, Duarte, California, United States

🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 15 locations

Sym022 (Anti-LAG-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Phase 1
Completed
Conditions
Metastatic Cancer
Solid Tumor
Lymphoma
Interventions
First Posted Date
2018-04-05
Last Posted Date
2021-02-18
Lead Sponsor
Symphogen A/S
Target Recruit Count
15
Registration Number
NCT03489369
Locations
🇺🇸

South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids, Michigan, United States

🇺🇸

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

🇨🇦

Princess Margaret Cancer Centre, Toronto, Ontario, Canada

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News

LAG-3 Inhibitors Show Promise in Cancer Immunotherapy, Market Expected to Surge

• The LAG-3 inhibitors market is poised for substantial growth, projected to exceed USD 3 billion by 2029, driven by increasing adoption in cancer therapy. • Opdualag, the first approved LAG-3 therapy, has demonstrated significant commercial success, generating substantial revenue and paving the way for further drug development. • Clinical trials are actively evaluating LAG-3 inhibitors in combination with other therapies, showing potential across various cancers, autoimmune disorders, and inflammatory diseases. • Several LAG-3 inhibitor candidates are in late-stage clinical trials, indicating a robust pipeline and growing interest from major pharmaceutical companies.

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