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Enlivex Therapeutics

Enlivex Therapeutics logo
🇮🇱Israel
Ownership
Public
Established
2005-10-01
Employees
49
Market Cap
-
Website
http://www.enlivex.com
Introduction

Enlivex Therapeutics Ltd. engages in the development of macrophage reprogramming immunotherapy products. It focuses on the development of Allocetra, a universal off-the-shelf cell therapy designed to reprogram macrophages into their homeostatic state. The company was founded by Dror Mevorach on January 22, 2012 and is headquartered in Ness Ziona, Israel.

Evaluation of Allocetra by Intra-articular Injection for the Treatment of Psoriatic Arthritis

Phase 1
Recruiting
Conditions
Arthritis, Psoriatic
Interventions
First Posted Date
2024-07-26
Last Posted Date
2025-04-23
Lead Sponsor
Enlivex Therapeutics Ltd.
Target Recruit Count
6
Registration Number
NCT06522035
Locations
🇮🇱

Carmel Medical Center, Haifa, Israel

🇮🇱

Meir Medical Center, Kfar Saba, Israel

🇮🇱

Rambam Medical Center, Haifa, Israel

and more 1 locations

Study of Intra-articular Allocetra in Knee Osteoarthritis

Phase 1
Active, not recruiting
Conditions
Osteoarthritis, Knee
Interventions
Other: Placebo
First Posted Date
2024-01-31
Last Posted Date
2025-04-23
Lead Sponsor
Enlivex Therapeutics Ltd.
Target Recruit Count
160
Registration Number
NCT06233474
Locations
🇩🇰

Sanos Clinic Herlev, Herlev, Denmark

🇩🇰

Sanos Clinic Syddanmark, Vejle, Denmark

🇮🇱

Hasharon Medical Center, Petach Tikva, Israel

and more 9 locations

A Phase 2b Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study, Evaluating Efficacy and Safety of Allocetra-OTS in Patients With Severe or Critical COVID-19 With Associated Acute Respiratory Distress Syndrome (ARDS)

Phase 2
Terminated
Conditions
Covid19
Interventions
Other: Placebo
First Posted Date
2021-06-11
Last Posted Date
2024-03-13
Lead Sponsor
Enlivex Therapeutics Ltd.
Target Recruit Count
12
Registration Number
NCT04922957
Locations
🇮🇱

Hadassah Ein Kerem Medical Center, Jerusalem, Israel

Study Evaluating Safety and Tolerability of Allocetra-OTS in Patients With COVID-19

Phase 1
Conditions
Covid19
Interventions
First Posted Date
2020-12-09
Last Posted Date
2021-08-18
Lead Sponsor
Enlivex Therapeutics Ltd.
Target Recruit Count
18
Registration Number
NCT04659304

A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients

Phase 2
Active, not recruiting
Conditions
Community-acquired Pneumonia
Sepsis
Cholecystitis, Acute
Urinary Tract Infections
Cholangitis Acute
Intraabdominal Infections
Interventions
Other: Placebo
First Posted Date
2020-11-03
Last Posted Date
2024-03-13
Lead Sponsor
Enlivex Therapeutics Ltd.
Target Recruit Count
160
Registration Number
NCT04612413
Locations
🇳🇱

Radboud UMC, Nijmegen, Netherlands

🇧🇪

CHU de Charleroi, Charleroi, Belgium

🇧🇪

Ziekenhuis Oost-Limburg, Genk, Belgium

and more 28 locations

Prevention of Sepsis-related Organ Dysfunction With Allocetra-OTS

Phase 1
Completed
Conditions
Organ Dysfunction Syndrome Sepsis
Interventions
Biological: Allocetra-OTS
First Posted Date
2019-04-24
Last Posted Date
2020-05-19
Lead Sponsor
Enlivex Therapeutics Ltd.
Target Recruit Count
10
Registration Number
NCT03925857
Locations
🇮🇱

Hadassah Medical Center, Jerusalem, Israel

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