National Institutes of Health (nih)

🇺🇸United States
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globenewswire.com
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Genomic Testing Market Poised to Reach Valuation of US$ 32.95 Billion By 2032

The global genomic testing market, valued at $14.52B in 2023, is projected to reach $32.95B by 2032, driven by innovations like CRISPR therapies, AI-driven tools, and long-read sequencing technologies. Major advancements include the first complete sequencing of the human Y chromosome and the deployment of portable sequencing devices globally. Investments in genomic research and precision medicine trials highlight the market's potential to transform healthcare through personalized treatments.
panewslab.com
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Dialogue with the founder of Pump.Science: When will the next DeSci+meme experiment ...

Benjels, co-founder of pump.science, discusses DeSci innovation, tokenizing drug IP, and plans to launch 20 new experimental tokens around Christmas, emphasizing the potential of DeSci to fund medical research and longevity technologies.

What's next for the psychedelics regulatory and clinical landscape?

The FDA's rejection of Lykos Therapeutics' NDA for MDMA therapy for PTSD highlights the need for consistent clinical trial outcomes. Psychedelics show potential for rapid-acting benefits but require proof of lasting impact. Future research will refine treatments, focusing on safety and long-term efficacy. The regulatory landscape may shift towards drug-therapy combinations, necessitating collaboration between the FDA and professional organizations. NIDA's funding of a ketamine study signals a positive shift in regulatory attitudes towards psychedelics. Each psychedelic compound has unique properties suited for specific conditions, with MDMA for PTSD and psilocybin for depression showing promise. Further research is needed to determine the longevity of therapeutic effects. Challenges in conducting psychedelic trials include safety screening and regulatory navigation, which can be addressed through rigorous trial design and collaboration.
globenewswire.com
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Daré Bioscience Reports Third Quarter 2024 Financial Results and Provides Company Update

Daré Bioscience reports financial results for Q3 2024, highlighting progress in its development programs including Ovaprene®, Sildenafil Cream 3.6%, DARE-HPV, DARE-VVA1, and DARE-PTB1, supported by grants and strategic funding. The company anticipates significant milestones in 2025.
medicine.washu.edu
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New drug targets for Alzheimer's identified from cerebrospinal fluid

Proteogenomic analysis identifies neurologically relevant regulation and causal proteins for Alzheimer’s disease. Supported by NIH, Chan Zuckerberg Initiative, Michael J. Fox Foundation, and others. Cruchaga received research support from GSK and Eisai, and is on the advisory board of Circular Genomics.
globenewswire.com
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Longeveron® Announces Third Quarter 2024 Financial Results and Provides Business Update

Longeveron reports 80% enrollment in Phase 2b ELPIS II trial for HLHS, positive FDA Type C meeting confirming trial's pivotal status, and Phase 2a CLEAR MIND trial data in Alzheimer’s disease presented at AAIC. Total Revenue for Q1-Q3 2024 increased 177% to $1.8M, with reduced operating expenses and sufficient cash to fund operations through Q4 2025.
globenewswire.com
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Neuroscience Market Projected to Reach USD 50.2 Billion by 2032

The neuroscience market, valued at USD 35.3 billion in 2023, is projected to reach USD 50.2 billion by 2032, growing at a CAGR of 4.0%. This expansion is driven by increasing awareness of neurological disorders, advancements in medical technology, and rising healthcare spending. Key technologies like Brain-Computer Interfaces (BCIs), AI, and machine learning are transforming diagnostics and treatments. Notable initiatives such as the BRAIN Initiative and China’s Brain Project are also contributing to market growth.
expresspharma.in
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Drug Repurposing: Unlocking access to rare solutions

Drug repurposing offers faster, affordable solutions for rare diseases, leveraging existing data and streamlined regulatory pathways. Advances in technology, like AI and big data, accelerate the process. Challenges include navigating regulatory frameworks and high costs, but collaboration and public-private partnerships can overcome these obstacles, making drug repurposing crucial for improving access to effective treatments.
nia.nih.gov
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Congressional Report 2024 | National Institute on Aging

Congressional Report 2024 highlights NIH's $100M increase for AD/ADRD research, focusing on immune dysfunction and precision therapeutics. NIA and NINDS are directed to report progress within 120 days. The report emphasizes the role of immune cells in AD/ADRD, including microglia, astrocytes, and peripheral immune cells, and explores potential therapeutic targets. NIH supports research on CAR immune cell therapy and precision medicine approaches for AD/ADRD, aiming to mitigate immune dysfunction and develop targeted therapies.
dovepress.com
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Barriers to Recruitment and Retention among Underrepresented Populatio

Clinical trials face challenges in US with underrepresentation of minorities, especially African Americans and Hispanics, due to barriers like mistrust, limited access, and socioeconomic factors. Despite policies by NIH, FDA, and CDC aiming to improve diversity, these efforts have not fully resolved underrepresentation. This issue can lead to less effective treatments for underrepresented groups and perpetuate healthcare disparities. The study identifies four main barriers from staff perspectives: lack of consistent decision-making structure, staff shortages, administrative burdens, and inadequate resources for recruitment and retention. Solutions include more systematic support from sponsoring agencies and cancer centers, use of AI for targeted recruitment, and community engagement strategies.
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