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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

An Observational Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis And Inadequate Response Or Intolerance to a First Anti-TNF Alpha Therapy

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-05-07
Last Posted Date
2016-08-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
90
Registration Number
NCT01592292

A Pharmacodynamic and Pharmacokinetic Study of RO5508887 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
Drug: RO5508887
First Posted Date
2012-05-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
42
Registration Number
NCT01592331

A Study of The Relative Bioavailability of Ritonavir-Boosted Danoprevir Fixed Dose Combination Tablets in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-05-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
42
Registration Number
NCT01592318

A Triple Combination Therapy Study of Boceprevir, Pegasys and Copegus in Previously Untreated Patients With Genotype 1 Chronic Hepatitis C

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
Drug: boceprevir
Drug: ribavirin (Copegus]
First Posted Date
2012-05-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
165
Registration Number
NCT01591460

A Drug-Drug Interaction Study of Ketoconazole, Rifampicin and Ritonavir-Boosted Atazanavir With Single-Dose RO5093151 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-05-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
51
Registration Number
NCT01591850

A Translational Study of Bevacizumab in Participants With Metastatic Colorectal Cancer

Phase 4
Completed
Conditions
Colorectal Neoplasms
Interventions
First Posted Date
2012-05-01
Last Posted Date
2019-01-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
128
Registration Number
NCT01588990
Locations
🇦🇺

Calvary North Adelaide; North Adeliade Oncology Centre, North Adelaide, South Australia, Australia

🇦🇺

Canberra Hospital, Garran, Australian Capital Territory, Australia

🇦🇺

Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia

and more 14 locations

A Study of RoActemra/Actemra (Tocilizumab) With or Without Methotrexate in Patients With Mild to Moderate Rheumatoid Arthritis With an Inadequate Response to Methotrexate

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2012-04-30
Last Posted Date
2015-07-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
77
Registration Number
NCT01587989

A Study of Potential Drug-Drug Interaction Between Efavirenz and Danoprevir With Low Dose Ritonavir in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2012-04-30
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT01588002

An Extension Study to Provide Continued Bevacizumab Therapy to Participants With Solid Tumors Who Were Previously Enrolled in a Roche/Genentech Sponsored Study

Phase 4
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2012-04-30
Last Posted Date
2020-11-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
95
Registration Number
NCT01588184
Locations
🇦🇹

A.Ö. LKH; Abt. für Lungenkrankheiten, Steyr, Austria

🇧🇷

Hospital Perola Byington, Sao Paulo, SP, Brazil

🇧🇷

Hospital A. C. Camargo; Oncologia, Sao Paulo, SP, Brazil

and more 70 locations
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