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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of Bevacizumab Versus Placebo in Combination With Carboplatin/Paclitaxel in Participants With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Previous Chemotherapy

Phase 3
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2011-06-02
Last Posted Date
2018-02-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
276
Registration Number
NCT01364012
Locations
🇨🇳

Beijing Hospital of Ministry of Health; Hematology, Beijing, China

🇨🇳

General Hospital of Chinese PLA; Department of Hematology, Beijing, China

🇨🇳

Beijing Chest Hospital; Oncology Department, Beijing, China

and more 14 locations

Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Participants With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Non-Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) and/or Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-05-27
Last Posted Date
2017-08-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
110
Registration Number
NCT01362062
Locations
🇮🇳

Excel Center, Guwahati, India

🇮🇳

Sir Gangaram Hospital, New Delhi, Delhi, India

🇮🇳

Healing Touch City Clinic, Chandigarh, India

and more 4 locations

A Study of RO5429083 in Patients With Metastatic and/or Locally Advanced, CD44-Expressing, Malignant Solid Tumors

Phase 1
Completed
Conditions
Neoplasms
Interventions
Drug: RO5429083
First Posted Date
2011-05-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
65
Registration Number
NCT01358903

A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

First Posted Date
2011-05-24
Last Posted Date
2024-06-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
4804
Registration Number
NCT01358877
Locations
🇺🇸

Texas Oncology - DFW, Dallas, Texas, United States

🇺🇸

The Mark H. Zangmeister Ctr; Mid Ohio Onc/Hem Inc., Columbus, Ohio, United States

🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

and more 552 locations

A Study of RO6807952 in Patients With Diabetes Mellitus Type 2

Phase 1
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: Placebo
Drug: RO6807952
First Posted Date
2011-05-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT01358929

An Observational Study of Lung Cancer Related Symptoms and Disease Control Rate in Patients With Non-Small Cell Lung Cancer Receiving First-Line Platinum-Based Chemotherapy With or Without Avastin (Bevacizumab)

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2011-05-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
156
Registration Number
NCT01358942

A Study on The Effect of Hepatic Impairment on The Pharmacokinetics of RO4917838

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: RO4917838
First Posted Date
2011-05-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
35
Registration Number
NCT01356550

A Study of MIRCERA for the Intrapetient Variability of Hemoglobin Levels in Patients With Chronic Renal Anemia (RIVAL)

Completed
Conditions
Anemia
First Posted Date
2011-05-19
Last Posted Date
2017-07-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1288
Registration Number
NCT01356589
Locations
🇬🇷

Ahepa Hospital; 1St Dept. of Medicine, Thessaloniki, Greece

🇬🇷

Kyanous Stavros of Patras, Renal Disease Therapy Unit, Patra, Greece

🇬🇷

General Hospital Tzanio ; Nephrology, Piraeus, Greece

and more 30 locations

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Non-biologic DMARDs

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2011-05-16
Last Posted Date
2014-06-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
39
Registration Number
NCT01353859

An Observational Study of Avastin (Bevacizumab) in Combination With Interferon Alpha-2a as First-Line Treatment in Patients With Advanced and/or Metastatic Renal Cell Carcinoma

Completed
Conditions
Renal Cell Cancer
First Posted Date
2011-05-11
Last Posted Date
2017-10-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
5
Registration Number
NCT01351571
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