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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Breast Cancer Progressing After First-Line Therapy With Avastin and Chemotherapy (TANIA)

Phase 3
Completed
Conditions
Breast Cancer
Interventions
Drug: bevacizumab [Avastin]
Drug: Chemotherapy
First Posted Date
2010-11-30
Last Posted Date
2016-02-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
494
Registration Number
NCT01250379

A Study to Assess the Incidence of EGFR Mutation in Patients With Newly Diagnosed Locally Advanced or Metastatic Non-Small Cell Lung Cancer in the UK, And of Tarceva (Erlotinib) as First-Line Therapy in EGFR Mutation Positive Patients.

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-11-30
Last Posted Date
2016-03-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
688
Registration Number
NCT01250119

A Study of RO5185426 in Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
Malignant Melanoma
Interventions
Drug: RO5185426
First Posted Date
2010-11-25
Last Posted Date
2016-08-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
374
Registration Number
NCT01248936

A Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in Participants With Relapsing Multiple Sclerosis

Phase 3
Completed
Conditions
Relapsing Multiple Sclerosis
Interventions
Drug: Ocrelizumab
Drug: Interferon beta-1a
Drug: Ocrelizumab-matching placebo
Drug: Interferon beta-1a-matching placebo
First Posted Date
2010-11-24
Last Posted Date
2024-03-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
821
Registration Number
NCT01247324
Locations
🇺🇸

Northwestern University; Dept. of Neurology, Chicago, Illinois, United States

🇺🇸

The Minneapolis Clinic of Neurology, Golden Valley, Minnesota, United States

🇺🇸

Uni of Vermont Medical Center;, Burlington, Vermont, United States

and more 138 locations

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-11-22
Last Posted Date
2015-11-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
65
Registration Number
NCT01245439

A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

Phase 2
Completed
Conditions
Coronary Heart Disease, Graft Occlusion, Vascular
Interventions
Drug: RO4905417
Drug: Placebo
First Posted Date
2010-11-22
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
384
Registration Number
NCT01245634

A Study of the Addition of Avastin (Bevacizumab) to Carboplatin and Paclitaxel Therapy in Patients With Ovarian Cancer

Phase 3
Completed
Conditions
Ovarian Cancer
Interventions
First Posted Date
2010-11-11
Last Posted Date
2016-06-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1021
Registration Number
NCT01239732

Analysis of HBV-Specific Immune Response in Patients With HBeAg Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a (40KD)) - Immunology Sub-Study of ML18253

Phase 3
Completed
Conditions
Hepatitis B, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2010-11-09
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
17
Registration Number
NCT01237496

A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25306)

Phase 3
Completed
Conditions
Schizophrenia
Interventions
First Posted Date
2010-11-05
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
597
Registration Number
NCT01235585

A Study of RO4917838 in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (NN25307)

Phase 3
Completed
Conditions
Schizophrenia
Interventions
Drug: RO4917838
Drug: Placebo
First Posted Date
2010-11-05
Last Posted Date
2015-06-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
595
Registration Number
NCT01235520
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