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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of Glucocorticoid Use to Evaluate Systematic Methylprednisolone Reduction in Patients With Rheumatoid Arthritis on Background RoActemra/Actemra (Tocilizumab) (ACT-ALONE)

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-10-13
Last Posted Date
2015-01-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
68
Registration Number
NCT01219933

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Breast Cancer

Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2010-10-06
Last Posted Date
2016-02-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
28
Registration Number
NCT01215123

A Study of RoActemra/Actemra (Tocilizumab) Plus DMARDs in Patients With Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-10-05
Last Posted Date
2015-12-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT01214733

A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer

Phase 3
Completed
Conditions
Pancreatic Cancer
Interventions
First Posted Date
2010-10-05
Last Posted Date
2014-08-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
607
Registration Number
NCT01214720

An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Patients With Chronic Kidney Disease on Dialysis (HORTENSIA)

Completed
Conditions
Anemia
First Posted Date
2010-10-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
419
Registration Number
NCT01213485

Study of ANA773 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) to Assess Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD)

Phase 1
Completed
Conditions
HCV Infection
Interventions
Drug: ANA773
Drug: Placebo
First Posted Date
2010-09-29
Last Posted Date
2012-11-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
75
Registration Number
NCT01211626
Locations
🇳🇱

Erasmus MC (EMC), Rotterdam, Netherlands

🇳🇱

Academisch Medisch Centrum (AMC), Amsterdam, Netherlands

🇳🇱

PRA Clinical Research Unit, Groningen, Netherlands

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Ankylosing Spondylitis Who Have Failed Treatment With NSAIDs

Phase 3
Terminated
Conditions
Spondylitis, Ankylosing
Interventions
Drug: Placebo
Biological: tocilizumab
First Posted Date
2010-09-27
Last Posted Date
2013-02-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
306
Registration Number
NCT01209702

A Study of Tocilizumab (RoActemra/Actemra) in Patients With Ankylosing Spondylitis Who Have Had an Inadequate Response to Previous Tumor Necrosis Factor (TNF) Antagonist Therapy

Phase 3
Terminated
Conditions
Spondylitis, Ankylosing
Interventions
Drug: Placebo
Drug: Tocilizumab
First Posted Date
2010-09-27
Last Posted Date
2013-01-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
113
Registration Number
NCT01209689

A Single Ascending And Multiple Ascending Dose Study of RO5271983 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo - MAD
Drug: RO5271983 - SAD
Drug: Placebo - SAD
Drug: RO5271983 - MAD
First Posted Date
2010-09-27
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
82
Registration Number
NCT01209221

A Study of Erlotinib [Tarceva] as Monotherapy or Intermittent Dosing With Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer. (TALISMAN)

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-09-17
Last Posted Date
2015-11-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
74
Registration Number
NCT01204697
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