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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of Avastin (Bevacizumab) in Combination With Fotemustine in Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2010-02-17
Last Posted Date
2018-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT01069627

PROPHESYS 3: Observational Study on Predictors of Response in Patients With Treatment-naïve Chronic Hepatitis C Initiated on Treatment With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b

Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Peginterferon alfa-2a [Pegasys]
Drug: Peginterferon alfa-2b [PegIntron®]
First Posted Date
2010-02-10
Last Posted Date
2016-08-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1656
Registration Number
NCT01066819

A Study of First or Second Line Treatment With Tarceva (Erlotinib) in Patients With Advanced Non-Small Cell Lung Cancer

Phase 4
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-02-10
Last Posted Date
2016-08-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
5
Registration Number
NCT01066884

A Study for Monthly Methoxy Polyethylene Glycol-Epoetin Beta Treatment in Patients With Chronic Renal Anaemia

Phase 4
Terminated
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2010-02-10
Last Posted Date
2017-11-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
33
Registration Number
NCT01066000
Locations
🇮🇩

Advent Hospital; Kidney and Hipertension, Bandung, Indonesia

🇮🇩

Sanglah Hospital; Kidney and Hipertension, Denpasar, Indonesia

🇮🇩

Rumah Sakit Pgi Cikini; Renal & Hypertension, Jakarta, Indonesia

and more 9 locations

PROPHESYS 2: An Observational Study on Predictors of Response in Treatment-naïve Patients With Chronic Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b

Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Peginterferon alfa-2a [Pegasys]
Drug: Peginterferon alfa-2b [PegIntron®]
First Posted Date
2010-02-10
Last Posted Date
2016-05-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
2343
Registration Number
NCT01066793

PRM-151 in the Prevention of Scarring Following Trabeculectomy

Phase 2
Completed
Conditions
Glaucoma
Interventions
Drug: PRM-151
Drug: Placebo
First Posted Date
2010-02-08
Last Posted Date
2022-04-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
124
Registration Number
NCT01064817
Locations
🇳🇱

UMC St. Radboud West, Nijmegen, Netherlands

🇬🇧

Oxford Eye Hosiptal, Oxford, United Kingdom

🇬🇧

St. Thomas, London, United Kingdom

and more 11 locations

A Study With Tocilizumab [RoActemra/Actemra] Monotherapy or in Combination With Methotrexate in Patients With Rheumatoid Arthritis (PICTURE)

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-02-05
Last Posted Date
2017-08-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
107
Registration Number
NCT01063062
Locations
🇪🇬

Banha Educational Hospital; Rheumatology, Banha, Egypt

🇪🇬

Kasr El Ainy Hospital; Rheumatology, Cairo, Egypt

🇪🇬

Manial Specialized Hospital; Rheumatology, Cairo, Egypt

and more 6 locations

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease

Phase 3
Terminated
Conditions
Cardiovascular Disease
Interventions
Drug: Dalcetrapib
Drug: Placebo
First Posted Date
2010-02-01
Last Posted Date
2020-03-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
936
Registration Number
NCT01059682

A Study of RO5024048 in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients With Chronic Hepatitis C Genotype 1 or 4

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: RO5024048
Drug: Ribavirin [Copegus]
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2010-01-27
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
168
Registration Number
NCT01057667

A Study of MabThera Added to Bendamustine or Chlorambucil in Patients With Chronic Lymphocytic Leukemia (MaBLe)

Phase 4
Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2010-01-26
Last Posted Date
2015-06-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
357
Registration Number
NCT01056510
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