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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Proof of Concept Study of the Safety, Tolerability, and Efficacy of Avastin (Bevacizumab) in Patients With Chemo-naive Chronic Lymphocytic Leukemia

Phase 2
Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2008-09-18
Last Posted Date
2014-06-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
2
Registration Number
NCT00754650

An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2008-09-11
Last Posted Date
2015-07-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1681
Registration Number
NCT00750880

A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.

Phase 3
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
First Posted Date
2008-09-01
Last Posted Date
2016-08-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
326
Registration Number
NCT00744367

A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Diet and Exercise.

Phase 3
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: placebo
Drug: taspoglutide
First Posted Date
2008-09-01
Last Posted Date
2016-07-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
373
Registration Number
NCT00744926

A Study of MabThera (Rituximab) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia.

Phase 2
Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2008-08-20
Last Posted Date
2017-08-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
97
Registration Number
NCT00738374
Locations
🇮🇹

Ospedale Cardarelli; Divisione Di Ematologia, Napoli, Campania, Italy

🇮🇹

A.O. Universitaria Policlinico S.Orsola-Malpighi Di Bologna, Bologna, Emilia-Romagna, Italy

🇮🇹

Arcispedale S. Anna; Sezione Di Ematologia, Ferrara, Emilia-Romagna, Italy

and more 17 locations

A Study of Avastin (Bevacizumab) Added to Interferon Alfa-2a (Roferon) Therapy in Patients With Metastatic Renal Cell Cancer With Nephrectomy

Phase 3
Completed
Conditions
Renal Cell Cancer
Interventions
Drug: Bevacizumab [Avastin]
Drug: Interferon alfa 2a [Roferon]
Drug: Placebo
First Posted Date
2008-08-20
Last Posted Date
2016-06-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
649
Registration Number
NCT00738530

A Study of Once Monthly Intravenous Mircera for the Maintenance Treatment of Dialysis Patients With Chronic Renal Anemia.

Phase 4
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2008-08-19
Last Posted Date
2017-12-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
132
Registration Number
NCT00737464
Locations
🇮🇳

Nizam's Institute of Medical Sciences; Nephrology, Hyderabad, India

🇮🇳

Wockhardt Hospital and Kidney Institute; Nephrology, Kolkata, India

🇮🇳

Meerut Kidney Hospital, Meerut, India

and more 14 locations

A Study of Monthly Subcutaneous (SC) Mircera for Maintenance Treatment of Participants With Chronic Kidney Disease on Peritoneal Dialysis

Phase 3
Completed
Conditions
Anemia
Interventions
First Posted Date
2008-08-19
Last Posted Date
2017-06-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
96
Registration Number
NCT00737477
Locations
🇫🇷

Arauco; Arauco Tours Bretonneau, Tours, France

🇫🇷

Centre Hospitalier; Hemodialyse, Annonay, France

🇫🇷

Ch Notre Dame Misericorde; Hemodialyse, Ajaccio, France

and more 49 locations

A Study of Two-Weekly Intravenous Mircera for the Treatment of Dialysis Patients With Chronic Renal Anemia Not Receiving ESA Therapy.

Phase 4
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2008-08-19
Last Posted Date
2016-06-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
189
Registration Number
NCT00737711

A Dose-Escalation Study of RO5083945 in Patients With Metastatic and/or Locally Advanced Malignant Epidermal Growth Factor Receptor (EGFR)+ Solid Tumors.

Phase 1
Completed
Conditions
Neoplasms
Interventions
Drug: RO5083945
First Posted Date
2008-07-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
102
Registration Number
NCT00721266
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