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Roche Holding AG
🇨🇭
Switzerland
Country
🇨🇭
Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Clinical Trials
Related News
A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate
Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Placebo
Biological: Rituximab
Drug: Methylprednisolone
Drug: Methotrexate
Drug: Folic acid or folate
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First Posted Date
2007-12-21
Last Posted Date
2015-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT00578305
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A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.
Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Methotrexate
Drug: rituximab [MabThera/Rituxan]
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First Posted Date
2007-12-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT00576433
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GAUSS: A Study of Obinutuzumab (RO5072759) in Patients With Indolent Non-Hodgkin's Lymphoma
Phase 2
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
Drug: obinutuzumab (RO5072759)
Drug: rituximab
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First Posted Date
2007-12-19
Last Posted Date
2014-08-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
175
Registration Number
NCT00576758
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A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Untreated Metastatic Colorectal Cancer.
Phase 2
Withdrawn
Conditions
Colorectal Cancer
Interventions
Drug: bevacizumab [Avastin]
Drug: Irinotecan
Drug: Leucovorin
Drug: 5 FU
Drug: Cetuximab
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First Posted Date
2007-12-19
Last Posted Date
2018-07-31
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT00577109
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A Study of Subcutaneous Mircera, Versus no Erythropoiesis-Stimulating Agent (ESA) Therapy, in the Treatment of Anemia in Patients With Chronic Kidney Disease After Kidney Transplant
Phase 4
Terminated
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
Drug: Supportive treatment
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First Posted Date
2007-12-19
Last Posted Date
2016-11-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1
Registration Number
NCT00576602
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OBELIX Study: A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Cancer of the Colon or Rectum.
Phase 4
Completed
Conditions
Colorectal Cancer
Interventions
Drug: bevacizumab [Avastin]
Drug: Oxaliplatin
Drug: Xeloda
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First Posted Date
2007-12-19
Last Posted Date
2015-08-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
205
Registration Number
NCT00577031
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A Study of Subcutaneous C.E.R.A. for the Treatment of Anemia in Pre-Dialysis Patients.
Phase 3
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [C.E.R.A.]
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First Posted Date
2007-12-19
Last Posted Date
2016-11-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
133
Registration Number
NCT00576628
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A Study of Intravenous Mircera in Dialysis Patients With Chronic Renal Disease and Anemia.
Phase 3
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
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First Posted Date
2007-12-19
Last Posted Date
2016-05-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
200
Registration Number
NCT00576303
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A Study of Avastin (Bevacizumab) and Transarterial Chemoembolisation (TACE) Treatment in Patients With Liver Cancer
Phase 2
Completed
Conditions
Liver Cancer
Interventions
Drug: Bevacizumab
Procedure: Transarterial chemoembolisation (TACE)
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First Posted Date
2007-12-19
Last Posted Date
2014-08-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT00576199
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A Study of Avastin (Bevacizumab) in Combination With Xeloda (Capecitabine) and Docetaxel in Patients With Inflammatory or Locally Advanced Breast Cancer.
Phase 2
Terminated
Conditions
Breast Cancer
Interventions
Drug: bevacizumab [Avastin]
Drug: Docetaxel
Drug: Xeloda
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First Posted Date
2007-12-19
Last Posted Date
2014-08-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
23
Registration Number
NCT00576901
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