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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study to Assess the Short Term Efficacy of Intravenous Ibandronate (Bondronat) in Participants With Metastatic Bone Pain Due to Breast Cancer

Phase 4
Completed
Conditions
Pain; Bone Neoplasms; Neoplasm Metastasis
Interventions
First Posted Date
2015-09-17
Last Posted Date
2015-09-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
182
Registration Number
NCT02553707

An Observational Study to Evaluate the Clinical Effectiveness, Quality of Life, Safety and Tolerability of Tocilizumab (TCZ) in Patients With Rheumatoid Arthritis (RA) in Daily Clinical Practice

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2015-09-17
Last Posted Date
2018-05-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
140
Registration Number
NCT02552940
Locations
🇧🇪

ASZ Aalst, Aalst, Belgium

🇧🇪

Reumacentrum Genk, Genk, Belgium

🇧🇪

AZ Damiaan, Oostende, Belgium

and more 19 locations

Observational Study to Evaluate Disease Course and Outcomes in Patients Treated With Esbriet (Pirfenidone) for Idiopathic Pulmonary Fibrosis (IPF) in Canada

Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Other: No intervention
First Posted Date
2015-09-17
Last Posted Date
2017-11-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
305
Registration Number
NCT02552849
Locations
🇨🇦

Edmonton Respiratory Consultants & Edmonton Sleep Lab, Edmonton, Alberta, Canada

🇨🇦

Kelowna Respiratory and Allergy Cllinic, Kelowna, British Columbia, Canada

🇨🇦

Mainra Rajesh R, Respirology, North Vancouver, British Columbia, Canada

and more 23 locations

A Trial to Evaluate the Efficacy of PRM-151 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Phase 2
Completed
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Other: placebo
Biological: PRM-151
First Posted Date
2015-09-16
Last Posted Date
2022-05-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
117
Registration Number
NCT02550873
Locations
🇩🇪

Justus-Liebig University Giessen, Giessen, Germany

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

UT - Southwestern Medical School, Dallas, Texas, United States

and more 15 locations

A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN)

First Posted Date
2015-09-15
Last Posted Date
2024-08-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
126
Registration Number
NCT02550652
Locations
🇺🇸

Emory Uni ; Division of Rheumatology, Atlanta, Georgia, United States

🇺🇸

Univ of California, San Diego, La Jolla, California, United States

🇺🇸

Stanford University Medical Center, Palo Alto, California, United States

and more 43 locations

Study of Intravenous RXDX-107 in Patients With Solid Tumors

Phase 1
Terminated
Conditions
Solid Tumor
Interventions
Drug: RXDX-107
First Posted Date
2015-09-14
Last Posted Date
2019-04-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
70
Registration Number
NCT02548390
Locations
🇺🇸

Florida Cancer Specialists, Sarasota, Florida, United States

🇺🇸

Johns Hopkins Medical Institute, Baltimore, Maryland, United States

🇺🇸

Tennessee Oncology, LLC, Nashville, Tennessee, United States

A Study to Evaluate Safety and Efficacy of Lebrikizumab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Phase 2
Completed
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Drug: Lebrikizumab
Drug: Placebo
First Posted Date
2015-09-11
Last Posted Date
2017-09-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
309
Registration Number
NCT02546700
Locations
🇺🇸

Centex Studies, Houston, Texas, United States

🇺🇸

Comprehensive Clinical Research Inc., Berlin, New Jersey, United States

🇺🇸

Clinical Research Inst. of Southern Oregon, Pc, Medford, Oregon, United States

and more 62 locations

A Single-Arm Study to Evaluate Administration of Lebrikizumab by Participants or Caregivers in the Home Setting

Phase 3
Withdrawn
Conditions
Asthma
Interventions
Drug: Lebrikizumab
Device: Prefilled Syringes
First Posted Date
2015-09-11
Last Posted Date
2018-04-25
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT02546869

An Observational Study to Evaluate the Effectiveness of Mircera Treatment for Renal Anemia in Pre-dialysis Participants With Chronic Kideny Disease (CKD)

Completed
Conditions
Kidney Disease, Chronic
Interventions
First Posted Date
2015-09-11
Last Posted Date
2017-06-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
393
Registration Number
NCT02547454
Locations
🇸🇮

Hospital Celje; Dept For Kidney Disease & Dialysis, Celje, Slovenia

🇸🇮

Splosna Bolnisnica Izola; Oddelek Za Nefrologijo, Izola, Slovenia

🇸🇮

Clinical Centre Ljubljana; Clinical Dep. For Nephrology, Ljubljana, Slovenia

and more 9 locations

A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In Participants With Relapsing Forms of Multiple Sclerosis

Phase 3
Completed
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Biological: 23-PPV
Biological: 13-PCV Booster
Biological: Influenza Vaccine
Biological: KLH
Drug: OCR
Biological: TT Vaccine
First Posted Date
2015-09-10
Last Posted Date
2024-03-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
102
Registration Number
NCT02545868
Locations
🇺🇸

The Minneapolis Clinic of Neurology, Golden Valley, Minnesota, United States

🇺🇸

Territory Neurology and Research Institute, Tucson, Arizona, United States

🇺🇸

North Central Neurology Associates, Cullman, Alabama, United States

and more 19 locations
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