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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study to Assess Whether Etrolizumab is a Safe and Efficacious Treatment for Participants With Moderately to Severely Active Crohn's Disease

Phase 3
Completed
Conditions
Crohn Disease
Interventions
Drug: Etrolizumab
Drug: Placebo
First Posted Date
2015-03-20
Last Posted Date
2022-11-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1035
Registration Number
NCT02394028
Locations
🇺🇸

Innovative Medical Research of South Florida, Aventura, Florida, United States

🇦🇹

LKH - Universitätsklinikum der PMU Salzburg, Salzburg, Austria

🇭🇷

Clinical Hospital Center Sestre Milosrdnice, Zagreb, Croatia

and more 324 locations

Human Epidermal Growth Factor Receptor 2 (HER2) Positive Unresectable Locally Advanced or Metastatic Breast Cancer Disease Registry Study

Completed
Conditions
Breast Cancer
Interventions
Other: No intervention
First Posted Date
2015-03-20
Last Posted Date
2024-02-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
311
Registration Number
NCT02393924
Locations
🇬🇧

Kent & Canterbury Hospital, Canterbury, United Kingdom

🇬🇧

Chesterfield Royal Hospital, Chesterfield, United Kingdom

🇬🇧

Royal Cornwall Hospital; Dept of Clinical Oncology, Cornwall, United Kingdom

and more 26 locations

BELOVA Data Collection: Safety and Efficacy of Frontline Bevacizumab Treatment in Participants With Ovarian Cancer 70 Years and Older

Completed
Conditions
Ovarian Cancer
Interventions
First Posted Date
2015-03-20
Last Posted Date
2019-07-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
76
Registration Number
NCT02393898
Locations
🇧🇪

UZ Antwerpen, Edegem, Belgium

🇧🇪

Sint Augustinus Wilrijk, Wilrijk, Belgium

🇧🇪

UZ Leuven Gasthuisberg, Leuven, Belgium

and more 23 locations

A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection

Phase 2
Completed
Conditions
Hepatitis B, Chronic
Interventions
Drug: Entecavir
Drug: Placebo
Drug: RO6864018
Drug: Tenofovir
First Posted Date
2015-03-18
Last Posted Date
2018-06-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
31
Registration Number
NCT02391805
Locations
🇲🇾

University Malaya Medical Center, Kuala Lumpur, Malaysia

🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

🇰🇷

Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of

and more 11 locations

Retrospective Data Collection: Post Study Treatment Anticancer Therapy From IMELDA MO22223

Completed
Conditions
Breast Cancer
Interventions
Other: No Intervention
First Posted Date
2015-03-09
Last Posted Date
2018-04-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT02383576
Locations
🇪🇸

Hospital Virgen de los Lirios; Servicio de Oncologia, Alcoy, Alicante, Spain

🇪🇸

Corporacio Sanitaria Parc Tauli; Servicio de Oncologia, Sabadell, Barcelona, Spain

🇧🇷

Hospital de Caridade de Ijui; Oncologia, Ijui, RS, Brazil

and more 29 locations

A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)

First Posted Date
2015-03-09
Last Posted Date
2020-11-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
135
Registration Number
NCT02383589
Locations
🇹🇷

Gülhane Military Medical Academy in Ankara, Ankara, Turkey

🇪🇸

Hospital de la Victoria, Malaga, Spain

🇺🇦

Dnipropetrovsk State Medical Academy, Dnipropterovsk, Ukraine

and more 65 locations

A Study to Assess the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Advanced Basal Cell Carcinoma (BCC)

Completed
Conditions
Basal Cell Carcinoma
Interventions
First Posted Date
2015-02-26
Last Posted Date
2020-10-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
50
Registration Number
NCT02371967
Locations
🇸🇪

Skånes Universitetssjukhus; Hudkliniken, Lund, Sweden

🇸🇪

SU/Sahlgrenska, Hudkliniken, Göteborg, Sweden

🇸🇪

Norrlands universitetssjukhus; Onkologkliniken, Umeå, Sweden

and more 1 locations

A Study of Atezolizumab in Combination With Carboplatin Plus (+) Nab-Paclitaxel Compared With Carboplatin+Nab-Paclitaxel in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Phase 3
Completed
Conditions
Carcinoma, Non-Squamous Non-Small Cell Lung
Interventions
First Posted Date
2015-02-20
Last Posted Date
2021-08-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
723
Registration Number
NCT02367781
Locations
🇺🇸

University of Miami School of Medicine - Sylvester at Deerfield, Deerfield Beach, Florida, United States

🇺🇸

Fort Wayne Med Oncology & Hematology Inc, Fort Wayne, Indiana, United States

🇺🇸

SCRI Florida Cancer Specialists East, West Palm Beach, Florida, United States

and more 129 locations

A Study of Atezolizumab in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-Paclitaxel Compared With Carboplatin + Nab-Paclitaxel in Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower131]

First Posted Date
2015-02-20
Last Posted Date
2022-03-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1021
Registration Number
NCT02367794
Locations
🇺🇸

Southern CA Permanente Med Grp, Bellflower, California, United States

🇺🇸

Kaiser Permanente Oakland Medical Center, Oakland, California, United States

🇺🇸

Kaiser Permanente - Santa Clara, Santa Clara, California, United States

and more 239 locations

A Study of Atezolizumab in Combination With Carboplatin Plus (+) Paclitaxel With or Without Bevacizumab Compared With Carboplatin+Paclitaxel+Bevacizumab in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

First Posted Date
2015-02-19
Last Posted Date
2021-09-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1202
Registration Number
NCT02366143
Locations
🇺🇸

Piedmont Cancer Institute, PC, Atlanta, Georgia, United States

🇺🇸

Univ of Pittsburgh Medical Ctr, Pittsburgh, Pennsylvania, United States

🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

and more 237 locations
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