Roche Holding AG
- Country
- 🇨🇭Switzerland
- Ownership
- Public
- Established
- 1896-01-15
- Employees
- 103.6K
- Market Cap
- $270.5B
- Website
- http://www.roche.com
Efficacy and Safety Study of Satralizumab (SA237) as Monotherapy to Treat Participants With Neuromyelitis Optica (NMO) and Neuromyelitis Optica Spectrum Disorder (NMOSD)
- Conditions
- Neuromyelitis Optica (NMO)NMO Spectrum Disorder (NMOSD)
- Interventions
- Drug: SatralizumabDrug: Placebo
- First Posted Date
- 2014-02-27
- Last Posted Date
- 2023-03-01
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 95
- Registration Number
- NCT02073279
- Locations
- 🇺🇸
University of Colorado Denver -; Neurology, Aurora, Colorado, United States
🇺🇸University of Miami UHealth Professional Arts Center, Miami, Florida, United States
🇺🇸Columbus Research and Wellness, Columbus, Georgia, United States
A Study Evaluating the Efficacy of Obinutuzumab and Bendamustine Treatment in Participants With Refractory or Relapsed Chronic Lymphocytic Leukemia
- Conditions
- Chronic Lymphocytic Leukemia
- Interventions
- First Posted Date
- 2014-02-25
- Last Posted Date
- 2020-02-07
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 72
- Registration Number
- NCT02071225
- Locations
- 🇪🇸
Hospital General Universitario de Elche; Servicio de Hematologia, Elche, Alicante, Spain
🇪🇸Hospital de Cabueñes; Servicio de Hematología y Hemoterapia, Gijon, Asturias, Spain
🇪🇸Hospital De Txagorritxu; Servicio de Hematologia, Vitoria, Alava, Spain
An Observational Study of Valcyte (Valganciclovir) in D+/R- Liver Transplant Recipients
- Conditions
- Cytomegalovirus Infections
- First Posted Date
- 2014-02-13
- Last Posted Date
- 2017-07-05
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 14
- Registration Number
- NCT02062294
- Locations
- 🇨🇭
Inselspital Bern; Viszerale Chirurgie und Medizin, Bern, Switzerland
🇨🇭HUG; Transplantation, Genève, Switzerland
🇨🇭Universitätsspital Zürich; Klinik für Gastroenterologie und Hepatologie, Zürich, Switzerland
A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax Combined With Chemotherapy in Participants With B-Cell Non-Hodgkin's Lymphoma (NHL) and DLBCL
- Conditions
- Lymphoma, Non-Hodgkin
- Interventions
- First Posted Date
- 2014-02-05
- Last Posted Date
- 2020-06-11
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 267
- Registration Number
- NCT02055820
- Locations
- 🇺🇸
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
🇦🇺Royal Melbourne Hospital, Parkville, Victoria, Australia
🇦🇹Medizinische Universität Wien, Wien, Austria
CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 2)
- Conditions
- Lymphocytic Leukemia, Chronic
- Interventions
- First Posted Date
- 2014-02-03
- Last Posted Date
- 2018-09-14
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 787
- Registration Number
- NCT02053610
A Study of Gantenerumab in Participants With Mild Alzheimer Disease
- First Posted Date
- 2014-01-31
- Last Posted Date
- 2023-02-10
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 389
- Registration Number
- NCT02051608
- Locations
- 🇺🇸
Richmond Behavioral Associates, Staten Island, New York, United States
🇨🇦Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
🇺🇸Banner Sun Health Research Insitute, Sun City, Arizona, United States
A Study of Subcutaneous (SC) Tocilizumab (RoActemra/Actemra) in Participants With Active Rheumatoid Arthritis (RA) and Inadequate Response to Disease-Modifying Anti-Rheumatic Drugs (DMARDs)
- Conditions
- Rheumatoid Arthritis
- Interventions
- First Posted Date
- 2014-01-28
- Last Posted Date
- 2018-04-13
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 133
- Registration Number
- NCT02046616
- Locations
- 🇩🇰
Aalborg Universitetshospital Nord, Reumatologisk Afdeling, Alborg, Denmark
🇩🇰Gentofte Hospital, Medicinsk Afd. C, Klinik for Gigt- og Rygsygdomme, Hellerup, Denmark
🇩🇰Glostrup Hospital, Reumatologisk Afdeling, Ambulatoriet, Glostrup, Denmark
A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent
- Conditions
- Rheumatoid Arthritis
- Interventions
- First Posted Date
- 2014-01-28
- Last Posted Date
- 2018-12-07
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 162
- Registration Number
- NCT02046603
- Locations
- 🇬🇧
Aberdeen Royal Infirmary, Aberdeen, United Kingdom
🇬🇧Royal Sussex County Hospital; Clinical Investigation Research Unit, Brighton, United Kingdom
🇬🇧University Hospital of Wales; Dept of Rhematology, Cardiff, United Kingdom
An Observational Study of Patients' Perception of Treatment With Erythropoiesis-Stimulating Agents in Patients With Chronic Kidney Disease Not on Dialysis (PERCEPOLIS)
- Conditions
- Anemia
- First Posted Date
- 2014-01-23
- Last Posted Date
- 2015-11-03
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 815
- Registration Number
- NCT02042833
Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.
- Conditions
- Healthy Volunteer, Muscular Atrophy, Spinal
- First Posted Date
- 2014-01-23
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 38
- Registration Number
- NCT02044029