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Moderna

Moderna logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
2010-01-01
Employees
5.6K
Market Cap
$30.3B
Website
http://www.modernatx.com
Introduction

Moderna, Inc. engages in the development of transformative medicines based on messenger ribonucleic acid (mRNA). Its product pipeline includes the following modalities: prophylactic vaccines, cancer vaccines, intratumoral immuno-oncology, localized regenerative therapeutics, systemic secreted therapeutics, and systemic intracellular therapeutics. The company was founded by Noubar B. Afeyan, Robert S. Langer, Jr., Derrick J. Rose and Kenneth R. Chien in 2010 and is headquartered in Cambridge, MA.

Clinical Trials

149

Active:49
Completed:67

Trial Phases

5 Phases

Phase 1:75
Phase 2:21
Phase 3:18
+2 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (121 trials with phase data)• Click on a phase to view related trials

Phase 1
75 (62.0%)
Phase 2
21 (17.4%)
Phase 3
18 (14.9%)
Not Applicable
3 (2.5%)
phase_1_2
2 (1.7%)
Phase 4
2 (1.7%)

A Study of mRNA-1345 Following a Primary Dose of a Licensed Protein Subunit Respiratory Syncytial Virus (RSV) Vaccine in Adult Participants ≥60 Years of Age

Not Applicable
Recruiting
Conditions
Respiratory Syncytial Virus
Interventions
First Posted Date
2025-08-12
Last Posted Date
2025-08-12
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
500
Registration Number
NCT07117487
Locations
🇺🇸

Velocity Clinical Research, Denver, Denver, Colorado, United States

🇺🇸

Indago Research & Health Center, Inc., Hialeah, Florida, United States

🇺🇸

Velocity Clinical Research, Savannah, Savannah, Georgia, United States

and more 8 locations

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

Not Applicable
Recruiting
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
Drug: mRNA-2808
First Posted Date
2025-08-11
Last Posted Date
2025-10-20
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
166
Registration Number
NCT07116616
Locations
🇺🇸

University of Alabama at Birmingham Hospital, Birmingham, Alabama, United States

🇺🇸

UCSF, San Francisco, California, United States

🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

and more 7 locations

A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Variant-containing Formulations

Not Applicable
Recruiting
Conditions
COVID-19
Interventions
Biological: mRNA-1283.251 Variant-containing Formulation
First Posted Date
2025-07-28
Last Posted Date
2025-10-14
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
832
Registration Number
NCT07089706
Locations
🇺🇸

DelRicht Research-Atlanta, Atlanta, Georgia, United States

🇺🇸

DelRicht Research-Baton Rouge, Baton Rouge, Louisiana, United States

🇺🇸

DelRicht Research-New Orleans, New Orleans, Louisiana, United States

and more 2 locations

A Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Solid Tumors

Phase 1
Not yet recruiting
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2025-03-17
Last Posted Date
2025-03-17
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
57
Registration Number
NCT06880536
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

🇺🇸

START San Antonio, San Antonio, Texas, United States

🇺🇸

START Mountain Region, West Valley City, Utah, United States

A Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Solid Tumors

Phase 1
Recruiting
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2025-03-17
Last Posted Date
2025-05-02
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
57
Registration Number
NCT06880549
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

🇺🇸

START San Antonio, San Antonio, Texas, United States

🇺🇸

START Mountain Region, West Valley City, Utah, United States

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News

Moderna's mRNA Flu Vaccines Show Promising Efficacy and Safety Data at IDWeek 2025

Moderna's seasonal flu vaccine mRNA-1010 demonstrated 26.6% relative vaccine efficacy compared to standard vaccines in adults aged 50 and above, meeting prespecified superiority criteria.

Moderna Advances mRNA-4359 as Late-Stage Oncology Asset with New Melanoma Data

Moderna presented new data on mRNA-4359, which is rapidly advancing to become one of the company's newest late-stage oncology assets.

Large French Study Confirms mRNA COVID-19 Vaccines Safe During Early Pregnancy, No Increased Birth Defect Risk

A comprehensive French study of over 527,000 infants found no increased risk of major congenital malformations among babies exposed to mRNA COVID-19 vaccines during the first trimester of pregnancy.

mRNA-Delivered Nanobodies Show Promise Against Colorectal Cancer in Preclinical Study

Researchers at JABSOM have developed an mRNA-based nanobody therapy that blocks PD-L1 and reduced colorectal cancer tumor growth by 50% in mouse models.

Activist Investor Shah Capital Calls for Novavax Sale Amid COVID Vaccine Market Share Struggles

Shah Capital, Novavax's second-largest shareholder with a 7.2% stake, has urged the company's board to pursue a sale, citing three consecutive years of poor COVID-19 vaccine performance.

COVID-19 Boosters Reduce Hospitalizations and Deaths by Up to 64% in Large Veterans Study

A large study of nearly 300,000 U.S. military veterans found that 2024-2025 COVID-19 mRNA boosters reduced emergency department visits by 29%, hospitalizations by 39%, and deaths by 64% compared to unvaccinated individuals.

Monash University Establishes Boston Hub to Accelerate Global Drug Discovery Partnerships

Monash University has established the Monash Boston Hub in Cambridge to deepen collaborations with North American and European biotech companies for drug discovery and health innovations.

Moderna Opens First UK mRNA Manufacturing Facility in Oxfordshire, Strengthening Pandemic Preparedness

Moderna's Innovation and Technology Centre in Harwell, Oxfordshire is now operational as the UK's first facility to manufacture mRNA vaccines onshore, capable of producing up to 100 million doses annually.

Moderna's Melbourne mRNA Facility Could Save Australia $4.8 Billion in Future Pandemic Costs

Australia's first fully integrated mRNA vaccine facility by Moderna could save the nation $4.8 billion during pandemics over the next 30 years, according to an Oxford Economics report.

Moderna Settles Patent Dispute with Alnylam Over COVID-19 Vaccine Technology

Moderna has settled patent infringement lawsuits filed by Alnylam Pharmaceuticals over alleged misuse of lipid nanoparticle technology in COVID-19 vaccines.

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