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Crinetics

Crinetics logo
🇺🇸United States
Ownership
Public
Established
2008-01-01
Employees
290
Market Cap
$4.3B
Website
http://www.crinetics.com
Introduction

Crinetics Pharmaceuticals, Inc. operates as a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Its product candidate, CRN00808, is an oral nonpeptide somatostatin agonist for the treatment of acromegaly. The firm is also developing other oral nonpeptide somatostatin agonists for neuroendocrine tumors and hyperinsulinism, as well as an oral nonpeptide ACTH antagonist for the treatment of Cushing's disease. The company was founded by R. Scott Struthers, Yun-Fei Zhu and Stephen F. Betz in 2008 and is headquartered in San Diego, CA.

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve)

Phase 2
Completed
Conditions
Acromegaly
Interventions
Drug: Placebo
First Posted Date
2019-01-03
Last Posted Date
2025-03-17
Lead Sponsor
Crinetics Pharmaceuticals Inc.
Target Recruit Count
13
Registration Number
NCT03792555
Locations
🇬🇷

General Hospital of Athens "Gennimatas", Athens, Greece

🇭🇺

Semmelweis University Faculty of Medicine, Budapest, Hungary

🇭🇺

University of Pécs Medical School, Pécs, Hungary

and more 8 locations

An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge)

Phase 2
Completed
Conditions
Acromegaly
Interventions
First Posted Date
2018-12-28
Last Posted Date
2025-02-17
Lead Sponsor
Crinetics Pharmaceuticals Inc.
Target Recruit Count
47
Registration Number
NCT03789656
Locations
🇺🇸

UCLA Gonda Diabetes Center, Los Angeles, California, United States

🇺🇸

Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 23 locations

Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Placebo Oral Solution
Drug: Placebo oral capsule
First Posted Date
2017-09-08
Last Posted Date
2018-08-29
Lead Sponsor
Crinetics Pharmaceuticals Inc.
Target Recruit Count
99
Registration Number
NCT03276858
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

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