Lexicon Pharmaceuticals

Lexicon Pharmaceuticals logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
1995-01-01
Employees
285
Market Cap
$621.7M
Website
http://www.lexpharma.com
Introduction

Lexicon Pharmaceuticals, Inc. engages in the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. Its drug candidates include: LX9211, an orally-delivered small molecule drug candidate, as a treatment for neuropathic pain, and Sotagliflozin, a treatment for heart failure and type 1 diabetes. The company...

Oral Contraceptive DDI Study

First Posted Date
2015-07-10
Last Posted Date
2016-03-02
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT02494609
Locations
🇺🇸

Lexicon Investigational Site, Dallas, Texas, United States

PK Study of Sotagliflozin in Subjects With Hepatic Impairment

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-06-15
Last Posted Date
2016-11-17
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT02471274
Locations
🇺🇸

Lexicon Investigational Site, Minneapolis, Minnesota, United States

Dose-ranging Study in Patients With Type 1 Diabetes Mellitus

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-06-02
Last Posted Date
2020-02-12
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
141
Registration Number
NCT02459899
Locations
🇺🇸

Lexicon Investigational Site, Manassas, Virginia, United States

Efficacy, Safety, and Tolerability Study of Sotagliflozin as Adjunct Therapy in Adult Patients With Type 1 Diabetes Mellitus Who Have Inadequate Glycemic Control With Insulin Therapy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2015-04-20
Last Posted Date
2020-02-12
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
782
Registration Number
NCT02421510
Locations
🇬🇧

Lexicon Investigational Site, Sheffield, United Kingdom

Efficacy, Safety, and Tolerability Study of Sotagliflozin as Adjunct Therapy in Adult Patients With Type 1 Diabetes Mellitus Who Have Inadequate Glycemic Control With Insulin Therapy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2015-03-10
Last Posted Date
2020-02-12
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
793
Registration Number
NCT02384941
Locations
🇨🇦

Lexicon Investigational Site, St. Laurent, Quebec, Canada

Efficacy and Safety of Sotagliflozin in Young Adult Patients With Type 1 Diabetes Mellitus and Elevated Hemoglobin A1C

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-03-10
Last Posted Date
2020-02-12
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
87
Registration Number
NCT02383940
Locations
🇺🇸

Lexicon Investigational Site, Salt Lake City, Utah, United States

Bioequivalence Study Between 400 mg LX4211 Tablets and 2 X 200 mg LX4211 Tablets

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-02-26
Last Posted Date
2015-10-02
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT02373046
Locations
🇺🇸

Lexicon Investigational Site, Dallas, Texas, United States

DDI Study With Multiple-dose LX4211 and Single Dose Digoxin

First Posted Date
2014-11-25
Last Posted Date
2015-07-09
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT02300350
Locations
🇺🇸

Lexicon Investigational Site, Dallas, Texas, United States

DDI Study With Multiple-dose LX4211 and Single Dose Rosuvastatin

First Posted Date
2014-11-25
Last Posted Date
2015-07-09
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT02300363
Locations
🇺🇸

Lexicon Investigational Site, Evansville, Indiana, United States

Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects

First Posted Date
2014-07-21
Last Posted Date
2016-09-07
Lead Sponsor
Lexicon Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT02195635
Locations
🇺🇸

Lexicon Investigational Site, Daytona Beach, Florida, United States

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