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The Methodist Hospital Research Institute

🇺🇸United States
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Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol

Phase 4
Completed
Conditions
Vancomycin
Prosthetic Joint Infection
Joint Diseases
Interventions
First Posted Date
2019-08-01
Last Posted Date
2023-03-15
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
23
Registration Number
NCT04042233
Locations
🇺🇸

Houston Methodist Hospital, Houston, Texas, United States

Neoadjuvant Atezolizumab in Cutaneous Melanoma

Phase 1
Recruiting
Conditions
Cutaneous Melanoma
Interventions
First Posted Date
2019-07-16
Last Posted Date
2023-06-28
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
20
Registration Number
NCT04020809
Locations
🇺🇸

Houston Methodist Hospital, Houston, Texas, United States

Brain Imaging in Men With Lower Urinary Tract Symptoms

Completed
Conditions
Voiding Disorders
Interventions
Diagnostic Test: Simultaneous functional MRI and urodynamic studies
Behavioral: Questionnaires
Other: Post Void Residual (PVR), Uroflow and Bladder Diary
Diagnostic Test: Urinalysis
First Posted Date
2019-06-19
Last Posted Date
2023-01-05
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
11
Registration Number
NCT03991429
Locations
🇺🇸

Houston Methodist Hospital, Houston, Texas, United States

Ocrelizumab for Psychosis by Autoimmunity

Phase 1
Recruiting
Conditions
Schizophrenia
Schizo-Affective Type of Psychosis
Interventions
Behavioral: Psychosis and cognitive assessments
Behavioral: Physical and neuro-cognitive evaluations
Diagnostic Test: Safety labs and electrocardiogram
Biological: Ocrelizumab infusion
First Posted Date
2019-06-03
Last Posted Date
2024-02-07
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
40
Registration Number
NCT03971487
Locations
🇺🇸

Houston Methodist Research Institute, Houston, Texas, United States

Durvalumab With Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer

Phase 2
Recruiting
Conditions
Breast Cancer
Interventions
First Posted Date
2019-01-29
Last Posted Date
2023-09-18
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
39
Registration Number
NCT03820141
Locations
🇺🇸

Houston Methodist Cancer Center, Houston, Texas, United States

Olaparib in Combination with Vorinostat in Patients with Relapsed/Refractory And/or Metastatic Breast Cancer

Phase 1
Recruiting
Conditions
Breast Cancer Metastatic
Breast Cancer
Interventions
First Posted Date
2018-11-15
Last Posted Date
2024-11-22
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
28
Registration Number
NCT03742245
Locations
🇺🇸

Houston Methodist Cancer Center, Houston, Texas, United States

Stroke Recovery and Music or No Music

Not Applicable
Conditions
Ischemic Stroke
Interventions
Other: Music listening
Other: Spoken word (language) listening
First Posted Date
2018-08-01
Last Posted Date
2018-08-01
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
20
Registration Number
NCT03608904
Locations
🇺🇸

Houston Methodist, Houston, Texas, United States

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

Phase 1
Recruiting
Conditions
Glioblastoma
Anaplastic Astrocytoma
Interventions
Drug: ADV/HSV-tk (gene therapy)
First Posted Date
2018-07-27
Last Posted Date
2024-11-25
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
62
Registration Number
NCT03603405
Locations
🇺🇸

Houston Methodist Neurological Institute, Houston, Texas, United States

Brain Targets in Patients With Bladder Emptying Difficulties

Not Applicable
Completed
Conditions
Neurogenic Bladder
Multiple Sclerosis
Voiding Dysfunction
Interventions
Device: Transcranial Rotating Permanent Magnet Stimulator (TRPMS)
First Posted Date
2018-07-02
Last Posted Date
2023-10-05
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
11
Registration Number
NCT03574610
Locations
🇺🇸

Houston Methodist Hospital, Houston, Texas, United States

Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery

Phase 2
Conditions
Prostate Cancer
High-risk Prostate Cancer
Interventions
Drug: HSV-Tk
Drug: Valacyclovir
Drug: Bicalutamide
Drug: Leuprolide Acetate
Radiation: Brachytherapy, External beam radiotherapy
Procedure: Radical prostatectomy
First Posted Date
2018-05-31
Last Posted Date
2021-04-06
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
60
Registration Number
NCT03541928
Locations
🇺🇸

Houston Methodist Hospital, Houston, Texas, United States

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