MedPath

Arvinas

Arvinas logo
🇺🇸United States
Ownership
Public
Established
2013-01-01
Employees
445
Market Cap
$1.7B
Website
http://www.arvinas.com
Introduction

Arvinas, Inc. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins. Its product candidates are ARV-110, a proteolysis targeting chimera (PROTAC) protein degrader that is in phase I clinical trial targeting the androgen receptor (AR) protein for the treatment of men with metastatic castration-resistant prostate cancer, ARV-471, and ARV-766, a PROTAC protein degrader targeting the estrogen receptor protein for the treatment of patients with metastatic ER positive/HER2 negative breast cancer. The company was founded in February 2013 and is headquartered in New Haven, CT.

Clinical Trials

3

Active:0
Completed:1

Trial Phases

2 Phases

Phase 1:2
Phase 2:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (3 trials with phase data)• Click on a phase to view related trials

Phase 1
2 (66.7%)
Phase 2
1 (33.3%)

A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

Phase 1
Recruiting
Conditions
KRAS G12D Mutation
Advanced Solid Cancer
Interventions
Drug: ARV-806
First Posted Date
2025-06-17
Last Posted Date
2025-08-11
Lead Sponsor
Arvinas Inc.
Target Recruit Count
159
Registration Number
NCT07023731
Locations
🇺🇸

Clinical Trial Site, Fairfax, Virginia, United States

A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.

Phase 1
Recruiting
Conditions
Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL)
Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL)
Interventions
First Posted Date
2024-05-01
Last Posted Date
2025-06-04
Lead Sponsor
Arvinas Inc.
Target Recruit Count
112
Registration Number
NCT06393738
Locations
🇪🇸

Clinical Trial Site, Salamanca, Spain

A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery

Phase 2
Completed
Conditions
Breast Cancer
Interventions
Procedure: Surgical resection of breast tumor
First Posted Date
2022-09-22
Last Posted Date
2025-08-29
Lead Sponsor
Arvinas Inc.
Target Recruit Count
152
Registration Number
NCT05549505
Locations
🇪🇸

Clinical Trial Site, Zaragoza, Spain

News

No news found

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