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James Felker
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United States
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Clinical Trials
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A Vaccine Trial for Low Grade Gliomas
Phase 2
Recruiting
Conditions
Low Grade Glioma
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First Posted Date
2015-02-06
Last Posted Date
2023-11-03
Lead Sponsor
James Felker
Target Recruit Count
25
Registration Number
NCT02358187
Locations
🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
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Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides with Imiquimod
Phase 1
Recruiting
Conditions
Ependymoma
Interventions
Biological: HLA-A2 restricted synthetic tumor antigen
Drug: Imiquimod
Other: enzyme-linked immunosorbent assay
Other: flow cytometry
Other: immunohistochemistry staining method
Other: laboratory biomarker analysis
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First Posted Date
2013-02-20
Last Posted Date
2024-12-06
Lead Sponsor
James Felker
Target Recruit Count
24
Registration Number
NCT01795313
Locations
🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
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A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas
Phase 1
Completed
Conditions
Newly Diagnosed Pediatric Pontine Glioma
Newly Diagnosed Pediatric High Grade Glioma
Recurrent Pediatric Low Grade Glioma
Recurrent Pediatric High Grade Glioma
Interventions
Biological: HLA-A2 restricted glioma antigen peptides vaccine
Biological: Poly-ICLC
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First Posted Date
2010-05-25
Last Posted Date
2024-12-06
Lead Sponsor
James Felker
Target Recruit Count
60
Registration Number
NCT01130077
Locations
🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
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