University Health Network

🇨🇦Canada

Country: 🇨🇦Canada

Ownership: Private

Established: 1999-01-01

Employees: 10K

Market Cap: -

Website: http://www.uhn.ca

Clinical Trials

Fitness Training Using WBEMS Among Individuals With SCI

Not Applicable

Completed

Conditions: Spinal Cord Injuries

First Posted Date: 2020-03-13

Last Posted Date: 2021-04-01

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 1

Registration Number: NCT04307017

Locations: 🇨🇦
Lyndhurst Centre, Toronto Rehabilitation Institute-UHN, Toronto, Ontario, Canada

Sleep Health Program for Patients With Chronic Pain

Not Applicable

Completed

Conditions: Chronic Pain
Sleep Disordered Breathing
Sleep

Interventions: Behavioral: Sleep Health Program for Participants with No/Mild Sleep Apnea
Behavioral: Sleep Health Program for Participants with Moderate/Severe Sleep Apnea

First Posted Date: 2020-03-06

Last Posted Date: 2021-12-10

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 40

Registration Number: NCT04299100

Locations: 🇨🇦
Mount Sinai Hospital, Department of Anesthesia, Toronto, Ontario, Canada
🇨🇦
Toronto Western Hopsital, Pain Clinic, Dept. of Anesthesia, Toronto, Ontario, Canada
🇨🇦
Toronto Rehab Institute (TRI), Toronto, Ontario, Canada

and more 2 locations

Comparison of Devices for Atrial Septal Defects Closure: A Pilot Study

Not Applicable

Recruiting

Conditions: Atrial Septal Defect

Interventions: Device: Occlutech Figulla Flex II®
Device: AMPLATZER™ Septal Occluder.
Device: GORE® CARDIOFORM ASD Occluder

First Posted Date: 2020-03-02

Last Posted Date: 2023-04-06

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 60

Registration Number: NCT04291898

Locations: 🇨🇦
Institut Universitaire de Cardiologie Et Pneumologie de Quebec/Hopital Laval, Québec, Quebec, Canada
🇨🇦
St. Paul's Hospital, Vancouver, British Columbia, Canada
🇨🇦
Institut de Cardiologie de Montreal (MHI), Montréal, Quebec, Canada

and more 1 locations

Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation

Not Applicable

Recruiting

Conditions: Thalassemia Major

Interventions: Dietary Supplement: Taurine
Other: Placebo

First Posted Date: 2020-03-02

Last Posted Date: 2023-10-03

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 60

Registration Number: NCT04291352

Locations: 🇨🇦
University Health Network, Toronto, Ontario, Canada

Canadian Adult Congenital Heart Disease Intervention Registry

Not yet recruiting

Conditions: Coarctation of Aorta
Transposition of Great Vessels
Atrial Septal Defect
Patent Foramen Ovale
Fontan
Percutaneous Pulmonary Valve Implantation
Tetralogy of Fallot

Interventions: Other: Participants undergoing ACHD intervention

First Posted Date: 2020-02-28

Last Posted Date: 2020-02-28

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 9000

Registration Number: NCT04288596

Locations: 🇨🇦
Toronto General Hospital, Toronto, Ontario, Canada

A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Adenocarcinoma, Non-Small Cell Lung Cancer and Squamous Cell Carcinoma of the Head and Neck to Correlate Clinical, Molecular and Immunologic Parameters With DNA Methylation

Phase 2

Withdrawn

Conditions: Pancreatic Ductal Adenocarcinoma
Non-small Cell Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Interventions: Biological: Durvalumab
Biological: Oleclumab

First Posted Date: 2020-02-10

Last Posted Date: 2020-11-17

Lead Sponsor: University Health Network, Toronto

Registration Number: NCT04262388

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

A Phase 2 Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Multi-Cancer Populations With Correlation to Clinical, Molecular and Immunologic Parameters With DNA MethylaTION

Phase 2

Withdrawn

Conditions: Non Small Cell Lung Cancer
Renal Cell Carcinoma

Interventions: Biological: Durvalumab
Biological: Oleclumab

First Posted Date: 2020-02-10

Last Posted Date: 2020-11-17

Lead Sponsor: University Health Network, Toronto

Registration Number: NCT04262375

Locations: 🇨🇦
Princess Margaret Cancer Centre, Toronto, Ontario, Canada

Cell-free DNA in Hereditary And High-Risk Malignancies

Active, not recruiting

Conditions: Hereditary Cancer Syndrome

Interventions: Genetic: Next generation sequencing (NGS)

First Posted Date: 2020-02-10

Last Posted Date: 2024-10-28

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 1416

Registration Number: NCT04261972

Locations: 🇨🇦
BC Cancer Agency, Vancouver, British Columbia, Canada
🇨🇦
Sinai Health System, Toronto, Ontario, Canada
🇨🇦
IWK Health Centre, Halifax, Nova Scotia, Canada

and more 4 locations

Restoring Upright Mobility After Spinal Cord Injury

Not Applicable

Completed

Conditions: Spinal Cord Diseases
Spinal Cord Injuries

First Posted Date: 2020-02-10

Last Posted Date: 2023-05-23

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 5

Registration Number: NCT04262414

Locations: 🇨🇦
Lyndhurst Centre, Toronto Rehabilitation Institute-UHN, Toronto, Ontario, Canada

DAPAgliflozin Sodium Water glucosE EffecTs in Patients at High Cardiovascular Risk

Phase 2

Recruiting

Conditions: Cardiovascular Risk Factor

Interventions: Drug: Dapagliflozin 10 MG
Drug: Placebo oral tablet

First Posted Date: 2020-02-06

Last Posted Date: 2023-05-17

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 50

Registration Number: NCT04258371

Locations: 🇨🇦
Renal Physiology Laboratory, Toronto, Canada

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