University Of Southampton

Scientists from the University of Sheffield and AstraZeneca developed MapDiff, an AI framework that outperforms existing methods for inverse protein folding, a critical process in designing therapeutic proteins.

New research from Penn State reveals that vitamin D deficiency in early pregnancy is associated with a fourfold increase in preterm birth rates and smaller infant size at delivery.

A systematic review of 102 randomized controlled trials found ADHD medications generally cause only small increases in blood pressure and heart rate in both children and adults.

The second annual London Biotechnology Show (#LBS25) builds on the success of its inaugural edition, which attracted over 3,000 attendees from 1,500 companies and featured 70+ sponsors and exhibitors.

• Cognition Therapeutics' oral drug candidate zervimesine (CT1812) demonstrates potential in treating dry AMD, with Phase 2 MAGNIFY trial data showing slower lesion growth rates compared to placebo. • Analysis of cerebrospinal fluid from Alzheimer's disease trials reveals zervimesine's ability to alter proteins and pathways associated with geographic atrophy and macular degeneration. • In vitro studies demonstrate zervimesine's capacity to normalize retinal pigment epithelial cell function when compromised by amyloid beta oligomers or oxidative stress.

A major clinical trial investigating β-hydroxy β-methylbutyrate (HMB) as a potential treatment for liver cirrhosis has been launched across eight UK hospitals, supported by £500,000 from NIHR.

The HARMONIE trial investigated the impact of nirsevimab on hospitalizations related to respiratory syncytial virus (RSV) in infants.