Kura Oncology

Kura Oncology logo
๐Ÿ‡บ๐Ÿ‡ธUnited States
Ownership
Public
Established
2014-01-01
Employees
142
Market Cap
$1.5B
Website
http://www.kuraoncology.com
Introduction

Kura Oncology, Inc. operates as a clinical-stage biopharmaceutical company, which engages in the research and development of medicines for the treatment of cancer. Its pipeline includes Tipifarnib, which is a Farnesyl transferase inhibitor for HRAS Mutant Solid Tumors, Chronic Myelomonocytic Leukemia, KO-947, which is an ERK inhibitor for MAPK Pathway Tumors...

Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy

First Posted Date
2018-10-25
Last Posted Date
2024-06-21
Lead Sponsor
Kura Oncology, Inc.
Target Recruit Count
296
Registration Number
NCT03719690
Locations
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University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, United States

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UCLA - Jonsson Comprehensive Cancer Center, Los Angeles, California, United States

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University of Chicago, Chicago, Illinois, United States

and more 98 locations

First-in-Human Study of KO-947 in Non-Hematological Malignancies

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2017-02-13
Last Posted Date
2021-09-20
Lead Sponsor
Kura Oncology, Inc.
Target Recruit Count
61
Registration Number
NCT03051035
Locations
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Mayo Clinic, Rochester, Minnesota, United States

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START Madrid-HM CIOCC, Madrid, Spain

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Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 2 locations

Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2016-06-21
Last Posted Date
2024-07-17
Lead Sponsor
Kura Oncology, Inc.
Target Recruit Count
44
Registration Number
NCT02807272
Locations
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Johns Hopkins University, Baltimore, Maryland, United States

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University of Pennsylvania Hospital, Philadelphia, Pennsylvania, United States

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Mayo Clinic Florida, Jacksonville, Florida, United States

and more 5 locations

Tipifarnib in Subjects With Myelodysplastic Syndromes

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2016-05-20
Last Posted Date
2024-07-31
Lead Sponsor
Kura Oncology, Inc.
Target Recruit Count
16
Registration Number
NCT02779777
Locations
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Dana-Farber Cancer Institute, Boston, Massachusetts, United States

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Columbia University Medical Center, New York, New York, United States

Investigation of Tipifarnib in Treatment of Subjects With Peripheral T-Cell Lymphoma (PTCL) That Have Not Responded to Standard Therapy

First Posted Date
2015-06-08
Last Posted Date
2024-06-26
Lead Sponsor
Kura Oncology, Inc.
Target Recruit Count
65
Registration Number
NCT02464228
Locations
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Hospital Universitari Vall d'Hebron, Barcelona, Spain

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Stanford University Medical Center, Palo Alto, California, United States

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Institut Catala d'Oncologia de Girona, Girona, Spain

and more 10 locations

Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations

First Posted Date
2015-03-10
Last Posted Date
2024-07-11
Lead Sponsor
Kura Oncology, Inc.
Target Recruit Count
63
Registration Number
NCT02383927
Locations
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Wihship Cancer Institute of Emory University, Atlanta, Georgia, United States

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Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, United States

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The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

and more 32 locations
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