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Immunovant Sciences GmbH

πŸ‡¨πŸ‡­Switzerland
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Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease

Phase 3
Recruiting
Conditions
Thyroid Eye Disease
Interventions
Other: Observational cohort study
First Posted Date
2022-08-26
Last Posted Date
2025-04-13
Lead Sponsor
Immunovant Sciences GmbH
Target Recruit Count
180
Registration Number
NCT05517447
Locations
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Site Number - 1508, Houston, Texas, United States

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Site Number - 3455, Tbilisi, Georgia

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Site Number - 3451, Tbilisi, Georgia

and more 41 locations

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

Phase 3
Active, not recruiting
Conditions
Thyroid Eye Disease
Interventions
Drug: Placebo
First Posted Date
2022-08-26
Last Posted Date
2025-06-12
Lead Sponsor
Immunovant Sciences GmbH
Target Recruit Count
100
Registration Number
NCT05517421
Locations
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Site Number - 1557, Beverly Hills, California, United States

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Site Number - 1539, Carlsbad, California, United States

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Site Number - 1502, Los Angeles, California, United States

and more 90 locations

Phase 3 Study to Assess the Efficacy and Safety of Batoclimab as Induction and Maintenance Therapy in Adult Participants With Generalized Myasthenia Gravis

Phase 3
Active, not recruiting
Conditions
Generalized Myasthenia Gravis
Interventions
First Posted Date
2022-06-03
Last Posted Date
2024-08-07
Lead Sponsor
Immunovant Sciences GmbH
Target Recruit Count
240
Registration Number
NCT05403541
Locations
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Site Number -1022, Phoenix, Arizona, United States

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Site Number -1029, Scottsdale, Arizona, United States

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Site Number -1002, Carlsbad, California, United States

and more 102 locations

To Assess the Efficacy and Safety of RVT-1401 in the Treatment of Warm Autoimmune Hemolytic Anemia (ASCEND-WAIHA).

Phase 2
Terminated
Conditions
Warm Autoimmune Hemolytic Anemia
Interventions
Drug: RVT-1401 680 mg/weekly
Drug: RVT-1401 340 mg/weekly
First Posted Date
2020-02-05
Last Posted Date
2022-07-28
Lead Sponsor
Immunovant Sciences GmbH
Target Recruit Count
5
Registration Number
NCT04253236
Locations
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University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States

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Norton Cancer Institute, Louisville, Kentucky, United States

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Massachusetts General Hospital Cancer Center - Hematology/Oncology, Boston, Massachusetts, United States

and more 18 locations

ASCEND GO-2: Study of RVT-1401 for the Treatment of Participants With Active, Moderate to Severe Graves' Ophthalmopathy ( GO )

Phase 2
Terminated
Conditions
Graves' Ophthalmopathy (GO)
Interventions
Other: Placebo (Administered via subcutaneous injection)
Drug: RVT-1401 (Administered via subcutaneous injection)
First Posted Date
2019-05-06
Last Posted Date
2022-09-22
Lead Sponsor
Immunovant Sciences GmbH
Target Recruit Count
65
Registration Number
NCT03938545
Locations
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Multispecialty Aesthetic Clinical Research Organziation (MACRO), Beverly Hills, California, United States

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Doheny Eye Center UCLA, Pasadena, California, United States

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University of Miami Miller School of Medicine Bascom Palmer Eye Institute, Miami, Florida, United States

and more 22 locations

Study of RVT-1401 for the Treatment of Patients With Moderate to Severe Active Graves' Ophthalmopathy (GO)

Phase 2
Completed
Conditions
Graves' Ophthalmopathy
Interventions
First Posted Date
2019-04-19
Last Posted Date
2022-01-24
Lead Sponsor
Immunovant Sciences GmbH
Target Recruit Count
7
Registration Number
NCT03922321
Locations
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UBC/VGH Eye Care Center, Vancouver, British Columbia, Canada

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Toronto Retina Institute, North York, Ontario, Canada

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University of Ottwa Eye Institute, Ottawa, Ontario, Canada

and more 1 locations

A Study of RVT-1401 in Myasthenia Gravis (MG) Patients

Phase 2
Completed
Conditions
Myasthenia Gravis
Interventions
Drug: Placebo
First Posted Date
2019-03-05
Last Posted Date
2023-12-20
Lead Sponsor
Immunovant Sciences GmbH
Target Recruit Count
17
Registration Number
NCT03863080
Locations
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IMC/Diagnostic and Medical Clinic, Mobile, Alabama, United States

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Phoenix Neurological Associates, Phoenix, Arizona, United States

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The Neurology Center of Southern California, Carlsbad, California, United States

and more 17 locations
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