MedPath

Q32 BIO INC.

Q32 BIO INC. logo
🇺🇸United States
Ownership
Private, Subsidiary
Established
2015-01-01
Employees
101
Market Cap
-
Website
http://www.homologymedicines.com

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

Phase 2
Withdrawn
Conditions
Lupus Nephritis (LN)
C3 (Complement Component 3) Glomerulopathy
IgA Nephropathy
Interventions
First Posted Date
2024-05-17
Last Posted Date
2025-04-20
Lead Sponsor
Q32 Bio Inc.
Target Recruit Count
30
Registration Number
NCT06419205
Locations
🇺🇸

Denver, Denver, Colorado, United States

🇺🇸

Minneapolis, Minneapolis, Minnesota, United States

🇺🇸

Las Vegas, Las Vegas, Nevada, United States

and more 2 locations

A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

Phase 2
Recruiting
Conditions
Alopecia Areata
Interventions
Drug: bempikibart (ADX-914)
First Posted Date
2023-08-30
Last Posted Date
2025-04-20
Lead Sponsor
Q32 Bio Inc.
Target Recruit Count
75
Registration Number
NCT06018428
Locations
🇺🇸

Scottsdale, Arizona, Scottsdale, Arizona, United States

🇺🇸

Fayetteville, Arkansas, Fayetteville, Arkansas, United States

🇺🇸

Hot Springs, Arkansas, Hot Springs, Arkansas, United States

and more 22 locations

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Phase 2
Active, not recruiting
Conditions
Atopic Dermatitis
Interventions
Drug: Placebo
First Posted Date
2022-08-19
Last Posted Date
2024-10-03
Lead Sponsor
Q32 Bio Inc.
Target Recruit Count
102
Registration Number
NCT05509023
Locations
🇺🇸

JBR Clinical Research, Salt Lake City, Utah, United States

🇺🇸

Dermatology of Seattle & Bellevue, Seattle, Washington, United States

🇺🇸

Dermatology Specialists of Spokane, Spokane, Washington, United States

and more 21 locations

Safety and Efficacy of HMI-203 in ERT-Treated Adults With MPS II

Phase 1
Withdrawn
Conditions
Mucopolysaccharidosis II
Interventions
Biological: Genetic HMI-203
First Posted Date
2022-02-14
Last Posted Date
2023-08-28
Lead Sponsor
Homology Medicines, Inc
Registration Number
NCT05238324
Locations
🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

🇺🇸

Lysosomal and Rare Disorders Research and Treatment Center, Inc., Fairfax, Virginia, United States

🇺🇸

UCSF Benioff Children's Hospital Oakland, Oakland, California, United States

and more 3 locations

Safety and Efficacy of HMI-103 in Participants With Classical PKU Due to PAH Deficiency

Phase 1
Terminated
Conditions
Phenylketonurias
Phenylketonuria
PAH Deficiency
Interventions
First Posted Date
2022-02-03
Last Posted Date
2023-10-10
Lead Sponsor
Homology Medicines, Inc
Target Recruit Count
3
Registration Number
NCT05222178
Locations
🇺🇸

The Community Health Clinic, Topeka, Indiana, United States

🇺🇸

Clinic for Special Children, Lancaster, Pennsylvania, United States

Natural History Clinical Study in Adult PKU

Terminated
Conditions
Phenylketonurias
PKU
First Posted Date
2021-02-24
Last Posted Date
2023-08-25
Lead Sponsor
Homology Medicines, Inc
Target Recruit Count
7
Registration Number
NCT04768348
Locations
🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

🇺🇸

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States

🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

and more 5 locations

Single and Multiple Ascending Dose Study of ADX-914 in Healthy Adult Volunteers

Phase 1
Completed
Conditions
Safety Issues
Interventions
Drug: Placebo
First Posted Date
2020-07-24
Last Posted Date
2022-07-28
Lead Sponsor
Q32 Bio Inc.
Target Recruit Count
42
Registration Number
NCT04485481
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

Long-Term Follow Up Study of Subjects Previously Administered HMI 102

Conditions
Phenylketonuria
PAH Deficiency
Interventions
Genetic: HMI-102
First Posted Date
2020-04-16
Last Posted Date
2022-06-30
Lead Sponsor
Homology Medicines, Inc
Target Recruit Count
21
Registration Number
NCT04348708
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

🇺🇸

Boston Children's Hospital, Boston, Massachusetts, United States

Gene Therapy Clinical Study in Adult PKU

Phase 1
Terminated
Conditions
Phenylketonurias
PAH Deficiency
Interventions
Genetic: HMI-102
First Posted Date
2019-05-16
Last Posted Date
2023-08-29
Lead Sponsor
Homology Medicines, Inc
Target Recruit Count
10
Registration Number
NCT03952156
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

🇺🇸

Children's Hospital of Orange County, Orange, California, United States

🇺🇸

The University of North Carolina At Chapel Hill, Chapel Hill, North Carolina, United States

and more 10 locations
© Copyright 2025. All Rights Reserved by MedPath