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University Medical Center Groningen

🇳🇱Netherlands

Country: 🇳🇱Netherlands

Ownership: Private

Established: 1614-01-01

Employees: 10K

Market Cap: -

Website: https://www.umcg.nl

Clinical Trials

Detection of PitNET Tissue During TSS Using Bevacizumab-800CW

Phase 1

Completed

Conditions: Pituitary Adenoma
Pituitary Macroadenoma
Pituitary Tumor

Interventions: Drug: Bevacizumab-IRDye800CW
Device: Molecular Fluorescence Endoscopy platform

First Posted Date: 2019-12-30

Last Posted Date: 2023-04-14

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 20

Registration Number: NCT04212793

Locations: 🇳🇱
University Medical Center Groningen, Groningen, Netherlands

POINTING: Clinical Cohort Study of Patients With Melanoma and NSCLC Receiving Checkpoint Inhibitors

Recruiting

Conditions: Melanoma
Non-Small Cell Lung Cancer

Interventions: Other: Standard-of-care procedures
Other: Study procedures

First Posted Date: 2019-12-11

Last Posted Date: 2024-05-03

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 3500

Registration Number: NCT04193956

Locations: 🇳🇱
NKI-AvL, Amsterdam, Netherlands
🇳🇱
University Medical Center Groningen, Groningen, Netherlands

The Dutch Parkinson and Cognition Study

Conditions: Parkinson Disease

First Posted Date: 2019-11-29

Last Posted Date: 2019-11-29

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 150

Registration Number: NCT04180865

Locations: 🇳🇱
University Medical Center Groningen, Groningen, Netherlands

Ovarian Cancer Treatment With a Liposome Formulated mRNA Vaccine in Combination With (Neo-)Adjuvant Chemotherapy

Phase 1

Terminated

Conditions: Ovarian Cancer

Interventions: Drug: W_ova1 Vaccine

First Posted Date: 2019-11-14

Last Posted Date: 2023-06-29

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 8

Registration Number: NCT04163094

Locations: 🇳🇱
UMCG, Groningen, Netherlands

Systemic Amoxicillin Plus Metronidazole in Peri-implantitis Treatment

Phase 4

Completed

Conditions: Periodontal Diseases
Peri-implantitis

Interventions: Drug: amoxicillin 500 mg + metronidazole 500 mg
Procedure: non-surgical periodontal and peri-implant treatment

First Posted Date: 2019-11-04

Last Posted Date: 2024-04-19

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 62

Registration Number: NCT04149327

Effect of Lumacaftor/Ivacaftor in Children With Cystic Fibrosis Homozygote for F508del on Small Airway Function

Completed

Conditions: Cystic Fibrosis in Children

First Posted Date: 2019-10-24

Last Posted Date: 2023-11-29

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 30

Registration Number: NCT04138589

Locations: 🇩🇪
Children's Hospital Marien Hospital Wesel, Düsseldorf, Germany
🇳🇱
Beatrix Children's Hospital, University Medical Center Groningen, Groningen, Netherlands

Biomarkers in Pediatric Congenital Heart Disease and PAH

Active, not recruiting

Conditions: Congenital Heart Disease
Pulmonary Arterial Hypertension

Interventions: Other: Blood test

First Posted Date: 2019-10-17

Last Posted Date: 2022-10-18

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 380

Registration Number: NCT04130243

Locations: 🇳🇱
University Medical Center Groningen, Groningen, Netherlands

Using Vedolizumab-800CW to Gain Insight Into Local Drug Distribution and Mucosal Target Cells in IBD Patients

Phase 1

Completed

Conditions: Crohn Disease
Colitis, Ulcerative

Interventions: Other: Fluorescence molecular imaging procedure without prior administration of vedolizumab-800CW
Drug: Fluorescence molecular imaging procedure using vedolizumab-800CW
Combination Product: Fluorescence molecular imaging procedure using vedolizumab-800CW with prior administration of unlabeled vedolizumab

First Posted Date: 2019-10-02

Last Posted Date: 2024-04-16

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 38

Registration Number: NCT04112212

Locations: 🇳🇱
University Medical Center Groningen, Groningen, Netherlands

Senescence and the Early Ageing Phenotype After Chemotherapy for Testicular Cancer: the SEA-CAT Study

Not Applicable

Recruiting

Conditions: Testicular Cancer

Interventions: Diagnostic Test: Skin biopsy
Diagnostic Test: Subcutaneous fat biopsy

First Posted Date: 2019-10-02

Last Posted Date: 2024-12-13

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 192

Registration Number: NCT04113122

Locations: 🇳🇱
University Medical Center Groningen, Groningen, Netherlands

Validation of the "ExSpiron©" in Patients With ALS

Not Applicable

Not yet recruiting

Conditions: Neuromuscular Diseases
Amyotrophic Lateral Sclerosis

Interventions: Device: ExSprion

First Posted Date: 2019-09-13

Last Posted Date: 2023-11-29

Lead Sponsor: University Medical Center Groningen

Target Recruit Count: 10

Registration Number: NCT04089696

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