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FORMA THERAPEUTICS, INC.

FORMA THERAPEUTICS, INC. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
2007-01-01
Employees
101
Market Cap
-
Website
http://www.formatherapeutics.com

A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

Phase 2
Recruiting
Conditions
Sickle Cell Disease
Interventions
First Posted Date
2024-01-10
Last Posted Date
2025-01-16
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
50
Registration Number
NCT06198712
Locations
🇨🇦

The Hospital for Sick Children, Toronto, Ontario, Canada

🇰🇪

Kombewa Clinical Research Centre, Kisumu, Kenya

🇰🇪

KEMRI-Walter-Reed Kericho, Kericho, Kenya

and more 12 locations

A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke

Phase 2
Recruiting
Conditions
Sickle Cell Disease
Interventions
First Posted Date
2023-07-20
Last Posted Date
2024-10-29
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
46
Registration Number
NCT05953584
Locations
🇮🇳

All India Institute of Medical Sciences (AIIMS), Raipur, Raipur, Chhattisgarh, India

🇮🇳

All India Institute of Medical Sciences-Delhi, Delhi, India

🇮🇳

Nirmal Hospital Pvt. Ltd., Gujarat, India

and more 6 locations

Study of the Effect of Etavopivat on Cerebral Hemodynamic Response in Children With Sickle Cell Disease

Phase 2
Recruiting
Conditions
Sickle Cell Disease
Interventions
First Posted Date
2023-02-13
Last Posted Date
2024-06-26
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
12
Registration Number
NCT05725902
Locations
🇺🇸

Emory University Children's Healthcare of Atlanta, Atlanta, Georgia, United States

A Study of Etavopivat for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS)

Phase 2
Terminated
Conditions
Very Low Risk, Low Risk, or Intermediate Risk MDS Per IPSS-R
Interventions
First Posted Date
2022-10-05
Last Posted Date
2024-12-17
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
45
Registration Number
NCT05568225
Locations
🇺🇸

Cedars-Sinai Medical Center, Plainsboro, New Jersey, United States

🇺🇸

Northwell Health, Plainsboro, New Jersey, United States

🇺🇸

Northwestern Memorial Hospital, Plainsboro, New Jersey, United States

and more 15 locations

A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease

Phase 2
Active, not recruiting
Conditions
Sickle Cell Disease
Thalassemia
Interventions
First Posted Date
2021-08-03
Last Posted Date
2025-05-21
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
60
Registration Number
NCT04987489
Locations
🇺🇸

[Legal] Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

UCSF Oakland Benioff ChildHosp, Oakland, California, United States

🇺🇸

[Legal] Children's Hospital of Orange County on behalf of CHOC Children's Hospital of Orange County, Orange, California, United States

and more 13 locations

A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)

Phase 3
Active, not recruiting
Conditions
Sickle Cell Disease
Interventions
First Posted Date
2020-11-12
Last Posted Date
2025-05-21
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
450
Registration Number
NCT04624659
Locations
🇫🇷

Hospices Civils de Lyon-Hopital Edouard Herriot, Lyon, France

🇩🇪

Univertatsklinikum Frankfurt, Frankfurt, Germany

🇪🇸

Hospital Clínico San Carlos, Madrid, Spain

and more 212 locations

A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic Steatohepatitis

Phase 1
Terminated
Conditions
Nonalcoholic Steatohepatitis (NASH)
Overweight or Obesity
Interventions
Drug: FT-4101 placebo
Other: Deuterated Water
First Posted Date
2019-07-02
Last Posted Date
2024-11-21
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
14
Registration Number
NCT04004325
Locations
🇺🇸

ProSciento, Inc., Chula Vista, California, United States

🇺🇸

Catalina Research Institute, Montclair, California, United States

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

Phase 1
Completed
Conditions
Healthy Volunteers
Sickle Cell Disease
Interventions
Drug: FT-4202/Placebo
First Posted Date
2019-01-24
Last Posted Date
2024-04-10
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
130
Registration Number
NCT03815695
Locations
🇺🇸

Pacific Research Partners (SCD subjects only), Oakland, California, United States

🇺🇸

St. Jude Children's Research Hospital (SCD subjects only), Memphis, Tennessee, United States

🇺🇸

Children's Healthcare of Atlanta (SCD subjects only), Atlanta, Georgia, United States

and more 15 locations

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Phase 1
Completed
Conditions
Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme)
Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas)
Cohort 3a and 3b: Chondrosarcoma
Cohort 4a and 4b: Intrahepatic Cholangiocarcinoma
Cohort 5a: Other Non-Central Nervous System Solid Tumors With IDH1 Mutations
Interventions
First Posted Date
2018-09-26
Last Posted Date
2023-11-18
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
93
Registration Number
NCT03684811
Locations
🇺🇸

Banner MD Anderson, Gilbert, Arizona, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

University of Miami, Sylvester Comprehensive Cancer Center, Miami, Florida, United States

and more 23 locations

Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutation

Phase 1
Completed
Conditions
Acute Myelogenous Leukemia
Myelodysplastic Syndrome
Acute Myeloid Leukemia
Interventions
Drug: FT-2102 (olutasidenib)
First Posted Date
2016-03-25
Last Posted Date
2024-11-05
Lead Sponsor
Forma Therapeutics, Inc.
Target Recruit Count
336
Registration Number
NCT02719574
Locations
🇺🇸

UCLA Medical Center, Los Angeles, California, United States

🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇦🇺

Box Hill Hospital, Monash University and Eastern Health Clinical School, Box Hill, Australia

and more 57 locations
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