University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Study of huCART19 for Very High-Risk (VHR) Subsets of Pediatric B-ALL

Phase 2

Completed

Conditions: Acute Lymphoblastic Leukemia

Interventions: Biological: huCART19

First Posted Date: 2019-01-03

Last Posted Date: 2025-06-05

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 100

Registration Number: NCT03792633

Locations: 🇺🇸
Children's Hospital of Pennsylvania, Philadelphia, Pennsylvania, United States

Evaluating Risk Factors and Biomarkers for Adaptation and Resilience to Spaceflight

Not Applicable

Completed

Conditions: Performance
Resilience
Mood
Stress, Psychological

Interventions: Behavioral: 8-Days in an Isolation, Confinement Unit

First Posted Date: 2018-12-24

Last Posted Date: 2025-04-06

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 32

Registration Number: NCT03786016

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment

Phase 4

Completed

Conditions: Obesity

Interventions: Behavioral: Behavioral Treatment
Drug: Placebo
Drug: Phentermine 15 MG

First Posted Date: 2018-12-19

Last Posted Date: 2025-03-11

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 147

Registration Number: NCT03779048

Locations: 🇺🇸
University of Pennsylvania Center for Weight and Eating Disorders, Philadelphia, Pennsylvania, United States

Partial Reinforcement II: Three Approaches to Maintenance Therapy for Chronic Insomnia

Phase 4

Completed

Conditions: Insomnia
Insomnia Chronic

Interventions: Drug: Zolpidem tartrate

First Posted Date: 2018-12-13

Last Posted Date: 2025-05-09

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 197

Registration Number: NCT03774810

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Remote Observed Dosing of Suboxone to Improve Clinical Practice

Phase 1

Completed

Conditions: Opioid-use Disorder
Opioid Dependence
Opiate Dependence

Interventions: Behavioral: Suboxone Remote Observed Dosing
Other: Suboxone Attention Control

First Posted Date: 2018-12-07

Last Posted Date: 2023-07-27

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 16

Registration Number: NCT03769025

Locations: 🇺🇸
University of Pennsylvania Treatment Research Center, Philadelphia, Pennsylvania, United States

Lentivirally Redirected CD123 Autologous T Cells in AML

Phase 1

Active, not recruiting

Conditions: Acute Myeloid Leukemia, Adult
Acute Myeloid Leukemia, Refractory
Acute Myeloid Leukemia, in Relapse

Interventions: Biological: CART123 cells; cyclophosphamide; fludarabine

First Posted Date: 2018-12-06

Last Posted Date: 2024-08-06

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 22

Registration Number: NCT03766126

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Oritavancin for Staphylococcus Aureus Infections in Opioid Users

Phase 4

Withdrawn

Conditions: Staphylococcus Aureus Endocarditis
Staphylococcus Aureus Bacteremia

Interventions: Drug: Oritavancin Injection

First Posted Date: 2018-12-03

Last Posted Date: 2022-04-06

Lead Sponsor: University of Pennsylvania

Registration Number: NCT03761953

Locations: 🇺🇸
Clinical Trials Unit. University of Pennsylvania, Philadelphia, Pennsylvania, United States

Imiquimod for Preventing Keloid Recurrence

Phase 2

Terminated

Conditions: Keloid

Interventions: Drug: Imiquimod 5% cream

First Posted Date: 2018-11-30

Last Posted Date: 2020-11-19

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 6

Registration Number: NCT03760250

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Evaluation of the Novel Use of Gamification With Alternative Goal-setting Experiences

Not Applicable

Completed

Conditions: Atherosclerotic Cardiovascular Disease

Interventions: Behavioral: Daily performance feedback
Behavioral: Choice + Immediate
Behavioral: Assigned + Gradual
Behavioral: Choice + Gradual
Behavioral: Assigned + Immediate
Behavioral: Gamification

First Posted Date: 2018-11-21

Last Posted Date: 2020-06-04

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 500

Registration Number: NCT03749473

Locations: 🇺🇸
Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania, United States

PET Imaging in Patients With Suspected Cardiac Sarcoidosis

Completed

Conditions: Cardiac Sarcoidosis

Interventions: Drug: Gallium-68 DOTATATE

First Posted Date: 2018-11-20

Last Posted Date: 2022-12-14

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT03746847

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

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