University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Default Options to Reduce Unnecessary Daily Imaging During Palliative Radiation

Not Applicable

Completed

Conditions: Cancer

Interventions: Behavioral: Default initiation

First Posted Date: 2017-04-12

Last Posted Date: 2019-12-09

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 1188

Registration Number: NCT03110692

Locations: 🇺🇸
University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States

Comparison of the Treatment of Refractory Bladder Pain Syndrome With DMSO and DMSO With Botulinum Toxin A

Early Phase 1

Completed

Conditions: Bladder Pain Syndrome

Interventions: Drug: DMSO
Drug: Botox

First Posted Date: 2017-04-06

Last Posted Date: 2017-06-09

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 2

Registration Number: NCT03103594

Novel Neural Circuit Biomarkers of Major Depression Response to CCBT

Not Applicable

Completed

Conditions: Depression, Unipolar
Depressive Disorder
Depression
Major Depressive Disorder

Interventions: Behavioral: Computer-Augmented Cognitive Behavioral Therapy

First Posted Date: 2017-03-30

Last Posted Date: 2024-12-05

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 132

Registration Number: NCT03096886

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Dendritic Cell Vaccination in Patients With Advanced Melanoma

Phase 1

Completed

Conditions: Melanoma

Interventions: Biological: Mature dendritic cell (DC) vaccine
Drug: Cyclophosphamide 300mg/m^2
Drug: Pembrolizumab

First Posted Date: 2017-03-28

Last Posted Date: 2024-12-24

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 5

Registration Number: NCT03092453

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

CART-PSMA-TGFβRDN Cells for Castrate-Resistant Prostate Cancer

Phase 1

Active, not recruiting

Conditions: Prostate Cancer

Interventions: Biological: CART-PSMA-TGFβRDN cells
Drug: Cyclophosphamide
Drug: Fludarabine

First Posted Date: 2017-03-24

Last Posted Date: 2024-04-26

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 23

Registration Number: NCT03089203

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Vascular Inflammation in Psoriasis - Apremilast

Phase 4

Completed

Conditions: Psoriasis
Cardiovascular Diseases

Interventions: Drug: Apremilast

First Posted Date: 2017-03-17

Last Posted Date: 2022-11-10

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 70

Registration Number: NCT03082729

Locations: 🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸
Center for Clinical Studies, Houston, Texas, United States
🇺🇸
Oregon Medical Research Center, Portland, Oregon, United States

and more 4 locations

Migraine and CVD Risk in Women

Not Applicable

Active, not recruiting

Conditions: Migraine

Interventions: Other: Mixed meal tolerance testing
Other: Skin conductance & cold pressor test
Other: Flow-mediated dilation testing

First Posted Date: 2017-03-16

Last Posted Date: 2023-09-28

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 30

Registration Number: NCT03081390

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Adrenergic System in Islet Transplantation

Early Phase 1

Active, not recruiting

Conditions: Type1diabetes
Hypoglycemia
Hypoglycemia Unawareness
Islet Cell Transplantation

Interventions: Drug: Placebo
Drug: Propranolol
Drug: Phentolamine

First Posted Date: 2017-03-15

Last Posted Date: 2023-08-30

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 11

Registration Number: NCT03079921

Locations: 🇺🇸
University of Pennsylvania - Institute for Diabetes, Obesity and Metabolism, Philadelphia, Pennsylvania, United States

Monitored Breathing Awareness Therapy for Insomnia Disorder in Older Adults

Not Applicable

Completed

Conditions: Insomnia

Interventions: Behavioral: MBAT

First Posted Date: 2017-03-07

Last Posted Date: 2017-07-18

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 20

Registration Number: NCT03072017

Colorectal Cancer Screening in a Community Health Setting

Not Applicable

Completed

Conditions: Cancer of the Colon

Interventions: Behavioral: Text-only
Behavioral: Text + Lottery

First Posted Date: 2017-03-07

Last Posted Date: 2019-02-20

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 281

Registration Number: NCT03072095

Locations: 🇺🇸
Family Practice & Counseling Network - Health Annex, Philadelphia, Pennsylvania, United States

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