UNIVERSITY OF SOUTHERN CALIFORNIA

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1880-01-01

Employees: 10K

Market Cap: -

Website: http://startusc.com

Clinical Trials

A Novel, Comprehensive Approach to Post-stroke Gait Rehabilitation

Phase 1

Recruiting

Conditions: CVA (Cerebrovascular Accident)

Interventions: Behavioral: Aerobic intensity-based walking
Behavioral: Step length biofeedback
Behavioral: Propulsive force biofeedback
Behavioral: Interlimb asymmetry biofeedback

First Posted Date: 2020-06-02

Last Posted Date: 2024-03-26

Lead Sponsor: University of Southern California

Target Recruit Count: 50

Registration Number: NCT04411303

Locations: 🇺🇸
University of Southern California, Los Angeles, California, United States

Effects of e-Cigarettes on Perceptions and Behavior - Substudy 1

Not Applicable

Completed

Conditions: Cigarette Use, Electronic
Cigarette Smoking
Vaping
Electronic Cigarette Use

Interventions: Drug: E-cigarette e-liquid

First Posted Date: 2020-05-22

Last Posted Date: 2023-07-11

Lead Sponsor: University of Southern California

Target Recruit Count: 124

Registration Number: NCT04399031

Locations: 🇺🇸
University of Southern California, Los Angeles, California, United States

Short-term Fasting Prior to PD-1/PD-L1 Inhibitor Therapy for of Advanced or Metastatic Skin Malignancy

Phase 1

Active, not recruiting

Conditions: Advanced Malignant Skin Neoplasm
Metastatic Malignant Skin Neoplasm

Interventions: Drug: Atezolizumab
Drug: Avelumab
Biological: Cemiplimab
Biological: Durvalumab
Biological: Nivolumab
Biological: Pembrolizumab
Other: Quality-of-Life Assessment
Other: Short-Term Fasting

First Posted Date: 2020-05-13

Last Posted Date: 2024-10-10

Lead Sponsor: University of Southern California

Target Recruit Count: 10

Registration Number: NCT04387084

Locations: 🇺🇸
Los Angeles General Medical Center, Los Angeles, California, United States
🇺🇸
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma

Phase 1

Terminated

Conditions: Locally Advanced Malignant Solid Neoplasm
Metastatic Pancreatic Adenocarcinoma
Stage IV Pancreatic Cancer AJCC v8
Unresectable Malignant Solid Neoplasm

Interventions: Biological: Agonistic Anti-OX40 Monoclonal Antibody INCAGN01949
Drug: VLP-encapsulated TLR9 Agonist CMP-001

First Posted Date: 2020-05-13

Last Posted Date: 2023-03-22

Lead Sponsor: University of Southern California

Target Recruit Count: 2

Registration Number: NCT04387071

Locations: 🇺🇸
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
🇺🇸
Hoag Memorial Hospital, Newport Beach, California, United States
🇺🇸
Lucile Packard Children's Hospital Stanford University, Palo Alto, California, United States

and more 1 locations

Low Frequency Subthalamic Nucleus Deep Brain Stimulation to Improve Verbal Fluency

Not Applicable

Completed

Conditions: Parkinson Disease

Interventions: Device: STN DBS off
Device: STN DBS 130Hz
Device: STN DBS 10Hz

First Posted Date: 2020-05-12

Last Posted Date: 2021-07-15

Lead Sponsor: University of Southern California

Target Recruit Count: 12

Registration Number: NCT04383665

Locations: 🇺🇸
Keck hospital of the University of Southern California, Los Angeles, California, United States

Cryoablation for Benign Gastrointestinal Anastomotic Strictures

Not Applicable

Conditions: Jejunal Stricture
Anastomotic Stricture of Small Intestine
Esophageal Stricture
Duodenal Stricture

Interventions: Procedure: Esophagogastroduodenoscopy with Balloon Dilatation
Device: Cryotherapy

First Posted Date: 2020-05-04

Last Posted Date: 2020-05-05

Lead Sponsor: University of Southern California

Target Recruit Count: 124

Registration Number: NCT04372784

Locations: 🇺🇸
Keck Hospital of USC, Los Angeles, California, United States

Baricitinib, Placebo and Antiviral Therapy for the Treatment of Patients With Moderate and Severe COVID-19

Phase 2

Terminated

Conditions: Symptomatic COVID-19 Infection Laboratory-Confirmed

Interventions: Drug: Hydroxychloroquine
Drug: Baricitinib
Drug: Placebo Administration

First Posted Date: 2020-05-04

Last Posted Date: 2021-05-26

Lead Sponsor: University of Southern California

Target Recruit Count: 6

Registration Number: NCT04373044

Locations: 🇺🇸
Los Angeles County-USC Medical Center, Los Angeles, California, United States
🇺🇸
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

In-Utero Endoscopic Correction of Spina Bifida

Not Applicable

Recruiting

Conditions: Neural Tube Defects
Spina Bifida
Myelomeningocele

Interventions: Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique
Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique

First Posted Date: 2020-04-27

Last Posted Date: 2023-06-15

Lead Sponsor: University of Southern California

Target Recruit Count: 110

Registration Number: NCT04362592

Locations: 🇺🇸
Wellington Regional Medical Center, Wellington, Florida, United States
🇺🇸
Hollywood Presbyterian Medical Center, Los Angeles, California, United States

Duration of Urinary Catheterization

Not Applicable

Recruiting

Conditions: Colorectal Surgery

Interventions: Other: Urinary catheter removal on postoperative day 3
Other: Urinary catheter removal on postoperative day 1

First Posted Date: 2020-04-24

Last Posted Date: 2023-05-12

Lead Sponsor: University of Southern California

Target Recruit Count: 176

Registration Number: NCT04359069

Locations: 🇺🇸
Keck Hospital of USC, Los Angeles, California, United States
🇺🇸
Los Angeles County Hospital (LAC/USC), Los Angeles, California, United States

Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients

Recruiting

Conditions: Anesthesia and Analgesia

Interventions: Behavioral: Diaphragmatic Breathing

First Posted Date: 2020-04-07

Last Posted Date: 2024-08-27

Lead Sponsor: University of Southern California

Target Recruit Count: 50

Registration Number: NCT04336579

Locations: 🇺🇸
Keck Hospital of USC, Los Angeles, California, United States

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