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Assistance Publique des Hôpitaux de Paris SA

🇫🇷France

Country: 🇫🇷France

Ownership: Private

Established: 1849-01-01

Employees: 10K

Market Cap: -

Website: http://www.aphp.fr

Clinical Trials

Use of a Respiratory Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Patients With Severe Confirmed COVID-19 Pneumonia

Not Applicable

Completed

Conditions: Pneumonia
Covid19

Interventions: Other: Usual antibiotic treatment
Procedure: Combined use of a respiratory broad panel multiplex PCR and procalcitonin

First Posted Date: 2020-04-06

Last Posted Date: 2021-08-03

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 194

Registration Number: NCT04334850

Locations: 🇫🇷
Intensive care department-Hospital Tenon, Paris, France

Cell Therapy Using Umbilical Cord-derived Mesenchymal Stromal Cells in SARS-CoV-2-related ARDS

Phase 1

Completed

Conditions: Severe Acute Respiratory Distress Syndrome
Severe Acute Respiratory Syndrome Coronavirus 2

Interventions: Biological: Umbilical cord Wharton's jelly-derived human
Other: NaCl 0.9%

First Posted Date: 2020-04-03

Last Posted Date: 2022-02-18

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 47

Registration Number: NCT04333368

Locations: 🇫🇷
Hôpital Pitié-Salpêtrière - APHP, Paris, France
🇫🇷
Hôpital Européen Georges Pompidou - APHP, Paris, France

CORIMUNO-19 - Tocilizumab Trial - TOCI (CORIMUNO-TOCI)

Phase 2

Completed

Conditions: Corona Virus Infection

Interventions: Drug: Tocilizumab

First Posted Date: 2020-04-02

Last Posted Date: 2025-06-12

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 228

Registration Number: NCT04331808

Locations: 🇫🇷
APHP- Hopital Tenon, Paris, France
🇫🇷
APHP - Beaujon, Paris, France
🇫🇷
APHP - Hopital Necker, Paris, France

and more 5 locations

Protective Role of Inhaled Steroids for Covid-19 Infection

Phase 3

Terminated

Conditions: Hospitalization in Respiratory Disease Department
Covid-19 Infection

First Posted Date: 2020-04-02

Last Posted Date: 2021-08-03

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 146

Registration Number: NCT04331054

Locations: 🇫🇷
Hôpital Bichat - Service de Pneumologie, Paris, France

ACE Inhibitors or ARBs Discontinuation in Context of COVID-19 Pandemic

Phase 3

Terminated

Conditions: History of Cardiovascular Disease Treated With RAS Blockers and With SARS-CoV-2 Infection

First Posted Date: 2020-04-01

Last Posted Date: 2021-04-09

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 44

Registration Number: NCT04329195

Locations: 🇫🇷
Cardiologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, France

Evaluation of the Role of Inflammatory and Structural Ultrasound Abnormalities by Explaining the Perspective of Patients With Psoriatic Arthritis

Not Applicable

Conditions: Psoriatic Arthritis

Interventions: Other: General evaluation
Other: Dermatological evaluation
Other: Rheumatological evaluation
Other: para clinical data
Other: Patient reported outcomes (PROs)

First Posted Date: 2020-03-30

Last Posted Date: 2020-04-06

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 100

Registration Number: NCT04325724

Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection

Phase 3

Terminated

Conditions: COVID-19

First Posted Date: 2020-03-27

Last Posted Date: 2021-02-25

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 30

Registration Number: NCT04325633

Locations: 🇫🇷
Urgences, Avicenne Hospital, Bobigny, France
🇫🇷
Réanimation médico-chirurgicale, Avicenne Hospital, Bobigny, France

Cohort Multiple Randomized Controlled Trials Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients - Sarilumab Trial - CORIMUNO-19 - SARI

Phase 2

Completed

Conditions: Corona Virus Infection

Interventions: Drug: Sarilumab

First Posted Date: 2020-03-27

Last Posted Date: 2025-06-12

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 239

Registration Number: NCT04324073

Locations: 🇫🇷
Kremlin Bicetre hospital APHP, Le Kremlin-Bicêtre, Ile De France, France
🇫🇷
NECKER Hospital, Paris, France
🇫🇷
Cochin Aphp, Paris, Ile De France, France

and more 1 locations

Cohort Multiple Randomized Controlled Trials Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients

Conditions: Corona Virus Infection

First Posted Date: 2020-03-27

Last Posted Date: 2020-04-01

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 1000

Registration Number: NCT04324047

Locations: 🇫🇷
Cochin Aphp, Paris, Ile De France, France
🇫🇷
Hegp Aphp, Paris, Ile De France, France
🇫🇷
Kremlin Bictre APHP, Le Kremlin-Bicêtre, Ile De France, France

Prevalence of Hypoglycaemia in Congenital Adrenal Insufficiency

Not Applicable

Completed

Conditions: Adrenal Insufficiency, Congenital

Interventions: Other: Continuous blood glucose measurement
Other: Measurement of capillary blood glucose

First Posted Date: 2020-03-26

Last Posted Date: 2024-12-17

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 9

Registration Number: NCT04322435

Locations: 🇫🇷
Hôpital Necker-Enfants Malades, Paris, France

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