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Arrowhead Pharmaceuticals

Arrowhead Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1989-01-01
Employees
525
Market Cap
$2.9B
Website
http://www.arrowheadpharma.com
Introduction

Arrowhead Pharmaceuticals, Inc. is a biopharmaceutical company, which engages in the development of medicines that treat intractable diseases by silencing the genes that cause them. The firms preclinical stage drug candidates include ARO-ANG3, ARO-AAT, ARO-APOC3, ARO-HIF2, ARO-HSD, ARO-Lung2, ARO-COV, and ARO-ENaC. The company was founded by Robert Bruce Stewart in 1989 and is headquartered in Pasadena, CA.

Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B Virus

Phase 2
Terminated
Conditions
Chronic Hepatitis B
Interventions
First Posted Date
2015-05-22
Last Posted Date
2017-12-05
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
4
Registration Number
NCT02452528
Locations
🇺🇸

Kaiser Permanente, San Francisco, California, United States

🇺🇸

Ichan School of Medicine at Mount Sinai, New York, New York, United States

🇺🇸

Univ. Of Miami School Of Medicine/Center For Liver Diseases, Miami, Florida, United States

and more 1 locations

A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Phase 1
Terminated
Conditions
Alpha-1 Antitrypsin Deficiency
Interventions
Drug: ARC-AAT Injection
Other: Placebo
First Posted Date
2015-02-16
Last Posted Date
2018-08-03
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
65
Registration Number
NCT02363946
Locations
🇳🇱

Leiden University Medical Center, Leiden, Netherlands

🇦🇺

Nucleus Network Ltd, Melbourne, Victoria, Australia

🇩🇪

Universitatsklinikum des Saarlandes, Homburg, Germany

and more 1 locations

Study of ARC-520 in Patient With Chronic Hepatitis B Virus

Phase 2
Withdrawn
Conditions
Chronic Hepatitis B
Interventions
Drug: ARC-520 Injection
First Posted Date
2015-01-28
Last Posted Date
2015-08-14
Lead Sponsor
Arrowhead Pharmaceuticals
Registration Number
NCT02349126
Locations
🇦🇺

Nucleus Network Ltd, Melbourne, Victoria, Australia

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

Phase 2
Terminated
Conditions
Hepatitis B, Chronic
Interventions
First Posted Date
2014-02-19
Last Posted Date
2019-07-05
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
58
Registration Number
NCT02065336
Locations
🇭🇰

Prince of Wales Hospital, Shatin, Hong Kong

🇭🇰

Queen Mary Hospital, Pokfulam, Hong Kong

Safety and Tolerability Study of ARC-520 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2013-06-07
Last Posted Date
2014-12-10
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
54
Registration Number
NCT01872065
Locations
🇦🇺

Nucleus Network Ltd., Melbourne, Victoria, Australia

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