DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer
Phase 1
Recruiting
- Conditions
- Small Cell Lung Cancer Extensive StageLarge Cell Neuroendocrine Carcinoma of the Lung
- Interventions
- First Posted Date
- 2023-01-11
- Last Posted Date
- 2025-05-22
- Lead Sponsor
- Legend Biotech USA Inc
- Target Recruit Count
- 41
- Registration Number
- NCT05680922
- Locations
- ๐บ๐ธ
Moffitt Cancer Center, Tampa, Florida, United States
๐บ๐ธUniversity of Kentucky - Markey Cancer Center, Lexington, Kentucky, United States
๐บ๐ธDana-Farber Cancer Institute, Boston, Massachusetts, United States
Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma
Phase 1
Recruiting
- Conditions
- Gastric CancerEsophageal CancerPancreatic CancerGastroesophageal-junction Cancer
- Interventions
- First Posted Date
- 2022-09-14
- Last Posted Date
- 2025-04-22
- Lead Sponsor
- Legend Biotech USA Inc
- Target Recruit Count
- 56
- Registration Number
- NCT05539430
- Locations
- ๐บ๐ธ
Moffitt Cancer Center, Tampa, Florida, United States
๐บ๐ธJohn Theurer Cancer Center at HackensackUMC, Hackensack, New Jersey, United States
๐บ๐ธVanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma
Phase 1
Active, not recruiting
- Conditions
- Peripheral T-Cell Lymphoma RefractoryCutaneous T-Cell Lymphoma RecurrentPeripheral T-Cell Lymphoma RecurrentCutaneous T-Cell Lymphoma RefractoryT-Cell Lymphoma
- Interventions
- Biological: LB1901
- First Posted Date
- 2021-01-15
- Last Posted Date
- 2023-10-03
- Lead Sponsor
- Legend Biotech USA Inc
- Target Recruit Count
- 50
- Registration Number
- NCT04712864
- Locations
- ๐บ๐ธ
Medical College of Wisconsin, Milwaukee, Wisconsin, United States
๐บ๐ธMD Anderson Cancer Center, Houston, Texas, United States
๐บ๐ธFred Hutchinson Cancer Research Center, Seattle, Washington, United States
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